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6EDU
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BU of 6edu by Molmil
B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 21c Fab VH domain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2018-08-11
公開日2018-10-17
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
Cell Host Microbe, 24, 2018
7RYU
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BU of 7ryu by Molmil
Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
分子名称: Ab1303 Fab heavy chain, Ab1303 Fab light chain
著者Yang, Z, Bjorkman, P.J.
登録日2021-08-26
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYV
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BU of 7ryv by Molmil
Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques
分子名称: Ab1573 Fab heavy chain, Ab1573 Fab light chain
著者Yang, Z, Bjorkman, P.J.
登録日2021-08-26
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7SC1
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BU of 7sc1 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, R40-1G8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, R40-1G8 Fab heavy chain, R40-1G8 Fab light chain, ...
著者Fan, C, Bjorkman, P.J.
登録日2021-09-26
公開日2022-02-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers.
Cell Host Microbe, 30, 2022
7N3G
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BU of 7n3g by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C098
分子名称: C098 Fab Heavy Chain, C098 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J, Barnes, C.O.
登録日2021-06-01
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7N3F
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BU of 7n3f by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C080
分子名称: C080 Fab Heavy Chain, C080 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J, Barnes, C.O.
登録日2021-06-01
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7N3E
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BU of 7n3e by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C032
分子名称: C032 Fab Heavy Chain, C032 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J, Barnes, C.O.
登録日2021-06-01
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7N3I
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BU of 7n3i by Molmil
Crystal structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment C098
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C098 Fab heavy chain, C098 Fab light chain, ...
著者Flyak, A.I, Bjorkman, P.J, Barnes, C.O.
登録日2021-06-01
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7N3H
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BU of 7n3h by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C099
分子名称: C099 Fab Heavy Chain, C099 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J, Barnes, C.O.
登録日2021-06-01
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7TFN
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BU of 7tfn by Molmil
Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-HIV-1 CD4bs antibody Fab Ab1303 - Heavy chain, ...
著者Yang, Z, Bjorkman, P.J.
登録日2022-01-06
公開日2022-01-19
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7TFO
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BU of 7tfo by Molmil
Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4 binding site antibody Ab1573 - Fab heavy chain, ...
著者Yang, Z, Bjorkman, P.J.
登録日2022-01-06
公開日2022-01-26
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7UCE
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BU of 7uce by Molmil
Structure of the anti-HIV-1 neutralizing antibody BG24 Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG24 Fab heavy chain, BG24 Fab light chain
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCG
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BU of 7ucg by Molmil
Structure of the DU422 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
分子名称: 10-1074 Fab heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCF
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BU of 7ucf by Molmil
Structure of the BG505 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7U0C
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BU of 7u0c by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.4
分子名称: HEPC3.4 Fab Heavy Chain, HEPC3.4 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J.
登録日2022-02-17
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
7U0B
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BU of 7u0b by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.1
分子名称: HEPC3.1 Fab Heavy Chain, HEPC3.1 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J.
登録日2022-02-17
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
7TQG
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BU of 7tqg by Molmil
Crystal Structure of IOMA Fab inferred germline
分子名称: IOMA iGL Fab Heavy Chain, IOMA iGL Fab Light Chain
著者Gristick, H.B, Bjorkman, P.J.
登録日2022-01-26
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.
Sci Immunol, 8, 2023
5CAY
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BU of 5cay by Molmil
Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120 core from ST strain of HIV-2, ...
著者Davenport, Y.W, Bjorkman, P.J.
登録日2015-06-30
公開日2015-12-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of an HIV-2 gp120 in Complex with CD4.
J.Virol., 90, 2015
5CJX
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BU of 5cjx by Molmil
Crystal structure of 8ANC195 Fab in complex with BG505 SOSIP.664 HIV-1 Env trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 heavy chain, ...
著者Scharf, L, Bjorkman, P.J.
登録日2015-07-15
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.584 Å)
主引用文献Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Cell, 162, 2015
4FQ1
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BU of 4fq1 by Molmil
Crystal Structure of PGT121 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain
著者Scharf, L, Bjorkman, P.J.
登録日2012-06-24
公開日2012-11-14
最終更新日2021-05-19
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
5D4K
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BU of 5d4k by Molmil
Crystal structure of the human polymeric Ig receptor (pIgR) ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Polymeric immunoglobulin receptor, SULFATE ION, ...
著者Stadtmueller, B.M, Bjorkman, P.J.
登録日2015-08-07
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins.
Elife, 5, 2016
5D6D
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BU of 5d6d by Molmil
Crystal structure of GASDALIE IgG1 Fc in complex with FcgRIIIa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor III-A, ...
著者Ahmed, A.A, Bjorkman, P.J.
登録日2015-08-12
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.
J.Struct.Biol., 194, 2016
4FQ2
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BU of 4fq2 by Molmil
Crystal Structure of 10-1074 Fab
分子名称: 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ...
著者Scharf, L, Bjorkman, P.J.
登録日2012-06-24
公開日2012-11-14
最終更新日2021-05-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
5D4Q
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BU of 5d4q by Molmil
Crystal structure of GASDALIE IgG1 Fc
分子名称: Ig gamma-1 chain C region, alpha-L-fucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ahmed, A.A, Bjorkman, P.J.
登録日2015-08-08
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural characterization of GASDALIE Fc bound to the activating Fc receptor Fc gamma RIIIa.
J.Struct.Biol., 194, 2016
4FQC
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BU of 4fqc by Molmil
Crystal Structure of PGT121 Fab Bound to a complex-type sialylated N-glycan
分子名称: Fab heavy chain, Fab light chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scharf, L, Bjorkman, P.J.
登録日2012-06-25
公開日2012-11-14
最終更新日2021-05-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012

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