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BU of 8de6 by Molmil

Oligomeric C9 in complex with aE11 Fab
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ...
著者	Bayly-Jones, C.
登録日	2022-06-20
公開日	2023-01-25
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9. Commun Biol, 6, 2023

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BU of 7uae by Molmil

Human meprin alpha (active state)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者	Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日	2022-03-12
公開日	2022-11-02
実験手法	ELECTRON MICROSCOPY (2.6 Å)
主引用文献	Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022

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BU of 7uac by Molmil

Human pro-meprin alpha (zymogen state)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Meprin A subunit alpha, ...
著者	Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日	2022-03-12
公開日	2022-11-02
実験手法	ELECTRON MICROSCOPY (2.7 Å)
主引用文献	Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022

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BU of 7uaf by Molmil

Human meprin alpha inhibitory complex with compound 10d (N~3~,N~3~-bis[(2H-1,3-benzodioxol-5-yl)methyl]-N-hydroxy-beta-alaninamide)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日	2022-03-12
公開日	2022-11-02
実験手法	ELECTRON MICROSCOPY (2.4 Å)
主引用文献	Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022

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BU of 7uai by Molmil

Meprin alpha helix in complex with fetuin-B
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日	2022-03-13
公開日	2022-11-02
実験手法	ELECTRON MICROSCOPY (2.8 Å)
主引用文献	Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022

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BU of 7uab by Molmil

Human pro-meprin alpha (zymogen state)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Bayly-Jones, C, Lupton, C.J, Fritz, C, Schlenzig, D, Whisstock, J.C.
登録日	2022-03-12
公開日	2022-11-02
実験手法	ELECTRON MICROSCOPY (3.7 Å)
主引用文献	Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor. Nat Commun, 13, 2022

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BU of 6u2j by Molmil

EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者	Pang, S.S, Bayly-Jones, C.
登録日	2019-08-20
公開日	2019-09-25
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (2.37 Å)
主引用文献	The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10, 2019

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BU of 7mp5 by Molmil

Autoinhibited neurofibrobmin
分子名称:	Isoform I of Neurofibromin
著者	Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
登録日	2021-05-04
公開日	2021-12-15
最終更新日	2022-03-16
実験手法	ELECTRON MICROSCOPY (5.6 Å)
主引用文献	The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1. Nat.Struct.Mol.Biol., 28, 2021

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BU of 7moc by Molmil

Neurofibromin core
分子名称:	Isoform I of Neurofibromin
著者	Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
登録日	2021-05-01
公開日	2021-12-15
最終更新日	2022-03-16
実験手法	ELECTRON MICROSCOPY (4.56 Å)
主引用文献	The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1. Nat.Struct.Mol.Biol., 28, 2021

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BU of 7mp6 by Molmil

Neurofibromin homodimer
分子名称:	Isoform I of Neurofibromin
著者	Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
登録日	2021-05-04
公開日	2021-12-15
最終更新日	2022-03-16
実験手法	ELECTRON MICROSCOPY (6.25 Å)
主引用文献	The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1. Nat.Struct.Mol.Biol., 28, 2021

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BU of 6u2w by Molmil

EM structure of MPEG-1(L425K) pre-pore complex bound to liposome
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者	Pang, S.S, Bayly-Jones, C.
登録日	2019-08-20
公開日	2019-09-25
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (3.63 Å)
主引用文献	The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10, 2019

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BU of 6u23 by Molmil

EM structure of MPEG-1(w.t.) soluble pre-pore
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者	Pang, S.S, Bayly-Jones, C.
登録日	2019-08-19
公開日	2019-09-25
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (3.49 Å)
主引用文献	The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10, 2019

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BU of 6u2l by Molmil

EM structure of MPEG-1 (L425K, beta conformation) soluble pre-pore complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者	Pang, S.S, Bayly-Jones, C.
登録日	2019-08-20
公開日	2019-09-25
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (2.83 Å)
主引用文献	The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10, 2019

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BU of 6u2k by Molmil

EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
著者	Pang, S.S, Bayly-Jones, C.
登録日	2019-08-20
公開日	2019-09-25
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (2.93 Å)
主引用文献	The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10, 2019

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BU of 7syf by Molmil

Reconstruction of full-length Prex-1 (PtdIns(3,4,5)P3-dependent Rac Exchanger 1)
分子名称:	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Endolysin chimera
著者	Lupton, C.J, Bayly-Jones, C, Ellisdon, A.M.
登録日	2021-11-24
公開日	2022-07-27
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (4.2 Å)
主引用文献	Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism. Nat.Struct.Mol.Biol., 29, 2022

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BU of 7rx9 by Molmil

Structure of autoinhibited P-Rex1
分子名称:	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, Endolysin chimera, SULFATE ION
著者	Ellisdon, A.M, Chang, Y.
登録日	2021-08-22
公開日	2022-08-10
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.22 Å)
主引用文献	Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism. Nat.Struct.Mol.Biol., 29, 2022

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BU of 6cxo by Molmil

Complement component-9
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ...
著者	Law, R.H.P, Spicer, B.A, Caradoc-Davies, T.T.
登録日	2018-04-03
公開日	2018-09-05
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018

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BU of 6dlw by Molmil

Complement component polyC9
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose
著者	Dunstone, M.A, Spicer, B.A, Law, R.H.P.
登録日	2018-06-03
公開日	2018-09-12
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (3.9 Å)
主引用文献	The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018

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件を2024-04-24に公開中

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