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STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
分子名称:	ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
著者	Barford, D, Hu, S.-H, Johnson, L.N.
登録日	1990-11-13
公開日	1992-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. J.Mol.Biol., 218, 1991

7GPB

STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
分子名称:	ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ...
著者	Barford, D, Hu, S.-H, Johnson, L.N.
登録日	1990-11-13
公開日	1992-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. J.Mol.Biol., 218, 1991

9GPB

THE ALLOSTERIC TRANSITION OF GLYCOGEN PHOSPHORYLASE
分子名称:	GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
著者	Barford, D, Johnson, L.N.
登録日	1990-12-17
公開日	1992-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	The allosteric transition of glycogen phosphorylase. Nature, 340, 1989

8A3T

S. cerevisiae APC/C-Cdh1 complex
分子名称:	Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者	Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J.
登録日	2022-06-09
公開日	2022-08-31
実験手法	ELECTRON MICROSCOPY (3.5 Å)
主引用文献	Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex To Be Published

8A61

S. cerevisiae apo phosphorylated APC/C
分子名称:	Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者	Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日	2022-06-16
公開日	2022-08-31
実験手法	ELECTRON MICROSCOPY (5.4 Å)
主引用文献	Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C To Be Published

8A5Y

S. cerevisiae apo unphosphorylated APC/C.
分子名称:	Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者	Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日	2022-06-16
公開日	2022-08-31
最終更新日	2023-07-26
実験手法	ELECTRON MICROSCOPY (4.9 Å)
主引用文献	Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states To Be Published

1GPA

STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
分子名称:	GLYCOGEN PHOSPHORYLASE A, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
著者	Barford, D, Hu, S.-H, Johnson, L.N.
登録日	1990-11-13
公開日	1992-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. J.Mol.Biol., 218, 1991

2HNQ

CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE 1B
分子名称:	PROTEIN-TYROSINE PHOSPHATASE-1B, TUNGSTATE(VI)ION
著者	Barford, D, Flint, A.J, Tonks, N.K.
登録日	1994-09-28
公開日	1994-12-20
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.85 Å)
主引用文献	Crystal structure of human protein tyrosine phosphatase 1B. Science, 263, 1994

2HNP

CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE 1B
分子名称:	PROTEIN-TYROSINE PHOSPHATASE-1B
著者	Barford, D, Flint, A.J, Tonks, N.K.
登録日	1994-09-19
公開日	1994-12-20
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.85 Å)
主引用文献	Crystal structure of human protein tyrosine phosphatase 1B. Science, 263, 1994

3KAE

Cdc27 N-terminus
分子名称:	CHLORIDE ION, GLYCEROL, Possible protein of nuclear scaffold, ...
著者	Barford, D, Zhang, Z, Roe, S.M.
登録日	2009-10-19
公開日	2010-03-23
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.298 Å)
主引用文献	Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture J.Mol.Biol., 397, 2010

1UWJ

The complex of mutant V599E B-RAF and BAY439006.
分子名称:	4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE
著者	Barford, D, Roe, S.M, Wan, P.T.C, Cancer Genome Project
登録日	2004-02-05
公開日	2004-03-19
最終更新日	2018-01-17
実験手法	X-RAY DIFFRACTION (3.5 Å)
主引用文献	Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf Cell(Cambridge,Mass.), 116, 2004

1UWH

The complex of wild type B-RAF and BAY439006.
分子名称:	4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE, CHLORIDE ION
著者	Barford, D, Roe, S.M, Wan, P.T.C, Cancer Genome Project
登録日	2004-02-05
公開日	2004-03-19
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.95 Å)
主引用文献	Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf Cell(Cambridge,Mass.), 116, 2004

1GZO

Structure of protein kinase B unphosphorylated
分子名称:	RAC-BETA SERINE/THREONINE PROTEIN KINASE
著者	Barford, D, Yang, J, Hemmings, B.A.
登録日	2002-05-24
公開日	2003-05-22
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.75 Å)
主引用文献	Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation Mol.Cell, 9, 2002

1GZK

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation
分子名称:	RAC-BETA SERINE/THREONINE PROTEIN KINASE
著者	Barford, D, Yang, J, Hemmings, B.A.
登録日	2002-05-23
公開日	2003-05-22
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation Mol.Cell, 9, 2002

1GZN

Structure of PKB kinase domain
分子名称:	RAC-BETA SERINE/THREONINE PROTEIN KINASE
著者	Barford, D, Yang, J, Hemmings, B.A.
登録日	2002-05-24
公開日	2003-05-22
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation Mol.Cell, 9, 2002

1WAO

PP5 structure
分子名称:	MANGANESE (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE 5
著者	Barford, D.
登録日	2004-10-27
公開日	2005-02-22
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5 Embo J., 24, 2005

6TKZ

Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
分子名称:	Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL, ...
著者	Barford, D.
登録日	2019-11-29
公開日	2020-01-22
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.64 Å)
主引用文献	Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022

6TKY

Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
分子名称:	Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL
著者	Barford, D, Fan, D, Cronin, N, Yang, J.
登録日	2019-11-29
公開日	2020-01-22
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022

6TM1

Crystal structure of the DHR2 domain of DOCK10 in complex with RAC3
分子名称:	Dedicator of cytokinesis protein 10, Ras-related C3 botulinum toxin substrate 3
著者	Barford, D, Fan, D, Cronin, N, Yang, J.
登録日	2019-12-03
公開日	2020-01-22
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (3.71 Å)
主引用文献	Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10 Biorxiv, 2022

1PTV

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE
分子名称:	O-PHOSPHOTYROSINE, PROTEIN TYROSINE PHOSPHATASE 1B
著者	Barford, D, Jia, Z.
登録日	1995-04-21
公開日	1996-08-01
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268, 1995

1PTT

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING TETRA-PEPTIDE (AC-DEPYL-NH2)
分子名称:	PHOSPHOTYROSINE-CONTAINING TETRA-PEPTIDE, PROTEIN TYROSINE PHOSPHATASE 1B
著者	Barford, D, Jia, Z.
登録日	1995-04-21
公開日	1996-08-01
最終更新日	2021-11-03
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268, 1995

1PTU

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2)
分子名称:	PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE, PROTEIN TYROSINE PHOSPHATASE 1B
著者	Barford, D, Jia, Z.
登録日	1995-04-21
公開日	1996-08-01
最終更新日	2021-11-03
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268, 1995

3ZV2

Human protein-tyrosine phosphatase 1b C215A, S216A mutant
分子名称:	Tyrosine-protein phosphatase non-receptor type 1
著者	Barford, D, Salmeen, A, Tonks, N.K.
登録日	2011-07-22
公開日	2011-08-31
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity. Cell, 147, 2011

6TNT

SUMOylated apoAPC/C with repositioned APC2 WHB domain
分子名称:	Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者	Barford, D, Yatskevich, S.
登録日	2019-12-10
公開日	2021-01-13
最終更新日	2021-07-28
実験手法	ELECTRON MICROSCOPY (3.78 Å)
主引用文献	Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation. Cell Rep, 34, 2021

1BZC

HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH TPI
分子名称:	4-CARBAMOYL-4-{[6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBONYL]-AMINO}-BUTYRIC ACID, PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE)
著者	Groves, M.R, Yao, Z.J, Jr Burke, T.R, Barford, D.
登録日	1998-10-27
公開日	1999-02-16
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics. Biochemistry, 37, 1998

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