6SP6
 
 | | Ultra-high Resolution Crystal Structure of the CTX-M-15 Extended-Spectrum beta-Lactamase in Complex with Taniborbactam (VNRX-5133) | | Descriptor: | (3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase, ... | | Authors: | Docquier, J.D, Pozzi, C, De Luca, F, Benvenuti, M, Mangani, S. | | Deposit date: | 2019-08-31 | | Release date: | 2020-01-22 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-beta-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.
J.Med.Chem., 63, 2020
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8JJ5
 | | Porcine uroplakin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Tetraspanin, ... | | Authors: | Oda, T, Yanagisawa, H, Kikkawa, M. | | Deposit date: | 2023-05-29 | | Release date: | 2023-06-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane.
Commun Biol, 6, 2023
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1JBA
 | | UNMYRISTOYLATED GCAP-2 WITH THREE CALCIUM IONS BOUND | | Descriptor: | CALCIUM ION, PROTEIN (GUANYLATE CYCLASE ACTIVATING PROTEIN 2) | | Authors: | Ames, J.B, Dizhoor, A.M, Ikura, M, Palczewski, K, Stryer, L. | | Deposit date: | 1999-04-03 | | Release date: | 1999-12-10 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional structure of guanylyl cyclase activating protein-2, a calcium-sensitive modulator of photoreceptor guanylyl cyclases.
J.Biol.Chem., 274, 1999
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8JCW
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 and NAM563 (dimerization mode I) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD1
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in Rco state | | Descriptor: | CHOLESTEROL, GLUTAMIC ACID, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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7SUU
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7SX6
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8JCZ
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode III) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD2
 | | Cryo-EM structure of G protein-free mGlu2-mGlu3 heterodimer in Acc state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JCV
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 (dimerization mode II) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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7SX7
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8JD6
 | | Cryo-EM structure of Gi1-bound metabotropic glutamate receptor mGlu4 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-3, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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1JQI
 | | Crystal Structure of Rat Short Chain Acyl-CoA Dehydrogenase Complexed With Acetoacetyl-CoA | | Descriptor: | ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, short chain acyl-CoA dehydrogenase | | Authors: | Battaile, K.P, Molin-Case, J, Paschke, R, Wang, M, Bennett, D, Vockley, J, Kim, J.-J.P. | | Deposit date: | 2001-08-07 | | Release date: | 2002-02-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal structure of rat short chain acyl-CoA dehydrogenase complexed with acetoacetyl-CoA: comparison with other acyl-CoA dehydrogenases.
J.Biol.Chem., 277, 2002
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1JQU
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1JR9
 | | Crystal Structure of manganese superoxide dismutases from Bacillus halodenitrificans | | Descriptor: | MANGANESE (II) ION, ZINC ION, manganese superoxide dismutase | | Authors: | Liao, J, Liu, M.Y, Chang, T, Li, M, LeGall, J, Gui, L.L, Zhang, J.P, Jiang, T, Liang, D.C, Chang, W.R. | | Deposit date: | 2001-08-13 | | Release date: | 2002-08-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Three-dimensional structure of manganese superoxide dismutase from Bacillus halodenitrificans, a component of the so-called "green protein".
J.Struct.Biol., 139, 2002
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8JCY
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode I) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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1JF1
 | | Crystal structure of HLA-A2*0201 in complex with a decameric altered peptide ligand from the MART-1/Melan-A | | Descriptor: | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ZINC ION, ... | | Authors: | Sliz, P, Michielin, O, Cerottini, J.C, Luescher, I, Romero, P, Karplus, M, Wiley, D.C. | | Deposit date: | 2001-06-19 | | Release date: | 2001-09-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes.
J.Immunol., 167, 2001
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8JD0
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of NAM563 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(1-methylpyrazol-4-yl)-7-[[(2~{S})-2-(trifluoromethyl)morpholin-4-yl]methyl]quinoline-2-carboxamide, CHOLESTEROL, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JCU
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 (dimerization mode I) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JCX
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 and NAM563 (dimerization mode II) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD5
 | | Cryo-EM structure of Gi1-bound mGlu2-mGlu4 heterodimer | | Descriptor: | 1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD3
 | | Cryo-EM structure of Gi1-bound mGlu2-mGlu3 heterodimer | | Descriptor: | 1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one, CHOLESTEROL, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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1JUB
 | | The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A | | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | | Deposit date: | 2001-08-24 | | Release date: | 2003-09-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
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8JD4
 | | Cryo-EM structure of G protein-free mGlu2-mGlu4 heterodimer in Acc state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8J51
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