8JD5

Cryo-EM structure of Gi1-bound mGlu2-mGlu4 heterodimer

Summary for 8JD5

• Entry DOI: 10.2210/pdb8jd5/pdb
• EMDB information: 36176 36226 36227 36286
• Descriptor: Metabotropic glutamate receptor 2, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: complex structure, gi1-bound mglu2-mglu4 heterodimer, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 316653.32

Authors

Wang, X.,Wang, M.,Xu, T.,Feng, Y.,Han, S.,Zhao, Q.,Wu, B. (deposition date: 2023-05-12, release date: 2023-06-21, Last modification date: 2023-10-18)

• Primary citation: Wang, X.,Wang, M.,Xu, T.,Feng, Y.,Shao, Q.,Han, S.,Chu, X.,Xu, Y.,Lin, S.,Zhao, Q.,Wu, B.; Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.; Cell Res., 33:762-774, 2023; PubMed: 37286794; DOI: 10.1038/s41422-023-00830-2

Experimental method

ELECTRON MICROSCOPY (3.6 Å)