8JD3

Cryo-EM structure of Gi1-bound mGlu2-mGlu3 heterodimer

Summary for 8JD3

• Entry DOI: 10.2210/pdb8jd3/pdb
• EMDB information: 36174
• Descriptor: Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 3, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (9 entities in total)
• Functional Keywords: complex structure, mglu2-mglu3 heterodimer with gi protein, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 286005.23

Authors

Wang, X.,Wang, M.,Xu, T.,Feng, Y.,Han, S.,Lin, S.,Zhao, Q.,Wu, B. (deposition date: 2023-05-12, release date: 2023-06-21, Last modification date: 2023-10-18)

• Primary citation: Wang, X.,Wang, M.,Xu, T.,Feng, Y.,Shao, Q.,Han, S.,Chu, X.,Xu, Y.,Lin, S.,Zhao, Q.,Wu, B.; Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.; Cell Res., 33:762-774, 2023; PubMed: 37286794; DOI: 10.1038/s41422-023-00830-2

Experimental method

ELECTRON MICROSCOPY (3.3 Å)