8TZ4
 
 | | Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction | | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter | | Authors: | Wright, N.J, Lee, S.-Y. | | Deposit date: | 2023-08-26 | | Release date: | 2024-03-13 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
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8TZ2
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8TZD
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8TZ1
 | | Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin | | Descriptor: | 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, ... | | Authors: | Wright, N.J, Lee, S.-Y. | | Deposit date: | 2023-08-26 | | Release date: | 2024-03-13 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (2.54 Å) | | Cite: | Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 20, 2024
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8TZ7
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8TZ5
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8TZ6
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8TZA
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8TZ3
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8TZ8
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8TZ9
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3S4S
 | | Crystal structure of CD4 mutant bound to HLA-DR1 | | Descriptor: | GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ... | | Authors: | Li, Y. | | Deposit date: | 2011-05-20 | | Release date: | 2011-09-21 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3S5L
 | | Crystal structure of CD4 mutant bound to HLA-DR1 | | Descriptor: | GLYCEROL, HA peptide, HLA class II histocompatibility antigen DR beta chain, ... | | Authors: | Li, Y. | | Deposit date: | 2011-05-23 | | Release date: | 2011-09-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
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5K5X
 | | Crystal structure of human PDGFRA | | Descriptor: | Platelet-derived growth factor receptor alpha, SULFATE ION | | Authors: | Yan, X.E, Liang, L, Yun, C.H. | | Deposit date: | 2016-05-24 | | Release date: | 2016-08-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.168 Å) | | Cite: | Structural and biochemical studies of the PDGFRA kinase domain
Biochem.Biophys.Res.Commun., 477, 2016
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4IL1
 | | Crystal Structure of the Rat Calcineurin | | Descriptor: | CALCIUM ION, Calmodulin, Calcineurin subunit B type 1, ... | | Authors: | Ye, Q, Faucher, F, Jia, Z. | | Deposit date: | 2012-12-28 | | Release date: | 2013-10-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of calcineurin activation by calmodulin.
Cell Signal, 25, 2013
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7FD2
 | | Cryo-EM structure of an alphavirus, Getah virus | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Liu, Z, Liu, C, Wang, A. | | Deposit date: | 2021-07-15 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Structure of infective Getah virus at 2.8 angstrom resolution determined by cryo-electron microscopy.
Cell Discov, 8, 2022
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6LYC
 | | Crystal structure of the NOD SIRPa complex with D4-2 | | Descriptor: | ACETIC ACID, D4-2, SIRPa of the NOD mouse strain | | Authors: | Murata, Y, Matsuda, M, Nakagawa, A, Matozaki, T. | | Deposit date: | 2020-02-14 | | Release date: | 2020-07-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Macrocyclic Peptide-Mediated Blockade of the CD47-SIRP alpha Interaction as a Potential Cancer Immunotherapy.
Cell Chem Biol, 27, 2020
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8EXE
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8EXF
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8J1I
 | | Crystal Structure of EphA8/SASH1 Complex | | Descriptor: | Ephrin type-A receptor 8, SAM and SH3 domain-containing protein 1 | | Authors: | Liu, W, Li, J, Ding, Y. | | Deposit date: | 2023-04-12 | | Release date: | 2024-02-28 | | Last modified: | 2024-09-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | SASH1: A Novel Eph Receptor Partner and Insights into SAM-SAM Interactions.
J.Mol.Biol., 435, 2023
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8K4Q
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8IQ0
 | | Crystal structure of hydrogen sulfide-bound superoxide dismutase in oxidized state | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ... | | Authors: | Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C. | | Deposit date: | 2023-03-15 | | Release date: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme.
Cell Rep, 42, 2023
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8IQ1
 | | Crystal structure of hydrogen sulfide-bound superoxide dismutase in reduced state | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ... | | Authors: | Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C. | | Deposit date: | 2023-03-15 | | Release date: | 2023-09-06 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme.
Cell Rep, 42, 2023
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6IGO
 | | Crystal structure of myelin protein zero-like protein 1 (MPZL1) | | Descriptor: | Myelin protein zero-like protein 1 | | Authors: | Yu, T. | | Deposit date: | 2018-09-25 | | Release date: | 2018-11-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.746 Å) | | Cite: | Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
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6IGT
 | | MPZL1 mutant - V145G, Q146K, P147T and G148S | | Descriptor: | Myelin protein zero-like protein 1 | | Authors: | Yu, T. | | Deposit date: | 2018-09-26 | | Release date: | 2018-11-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.404 Å) | | Cite: | Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
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