Crystal structure of human PDGFRA

Summary for 5K5X

DescriptorPlatelet-derived growth factor receptor alpha, SULFATE ION (3 entities in total)
Functional Keywordstyrosine kinase, autoinhibition, transferase
Biological sourceHomo sapiens (Human)
Cellular locationCell membrane ; Single- pass type I membrane protein  P16234
Total number of polymer chains1
Total molecular weight40876.92
Yan, X.E.,Liang, L.,Yun, C.H. (deposition date: 2016-05-24, release date: 2016-08-17, Last modification date: 2017-10-04)
Primary citation
Liang, L.,Yan, X.E.,Yin, Y.,Yun, C.H.
Structural and biochemical studies of the PDGFRA kinase domain
Biochem.Biophys.Res.Commun., 477:667-672, 2016
PubMed: 27349873 (PDB entries with the same primary citation)
DOI: 10.1016/j.bbrc.2016.06.117
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.226100 9.2% 9.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-23