6LYC

Crystal structure of the NOD SIRPa complex with D4-2

Summary for 6LYC

Entry DOI	10.2210/pdb6lyc/pdb
Descriptor	SIRPa of the NOD mouse strain, D4-2, ACETIC ACID, ... (4 entities in total)
Functional Keywords	complex, cell adhesion
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	15231.00
Authors	Murata, Y.,Matsuda, M.,Nakagawa, A.,Matozaki, T. (deposition date: 2020-02-14, release date: 2020-07-01, Last modification date: 2023-11-29)
Primary citation	Hazama, D.,Yin, Y.,Murata, Y.,Matsuda, M.,Okamoto, T.,Tanaka, D.,Terasaka, N.,Zhao, J.,Sakamoto, M.,Kakuchi, Y.,Saito, Y.,Kotani, T.,Nishimura, Y.,Nakagawa, A.,Suga, H.,Matozaki, T. Macrocyclic Peptide-Mediated Blockade of the CD47-SIRP alpha Interaction as a Potential Cancer Immunotherapy. Cell Chem Biol, 27:1181-1191.e7, 2020 Cited by PubMed: 32640189 DOI: 10.1016/j.chembiol.2020.06.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.36 Å)

Structure validation