6EAD
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6EAF
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6EAK
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6EAE
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6EAJ
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5TP3
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5TOJ
| Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... | Authors: | Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. | Deposit date: | 2016-10-17 | Release date: | 2017-02-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
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5TOK
| Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-L66 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... | Authors: | Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. | Deposit date: | 2016-10-17 | Release date: | 2017-02-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
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6EAG
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6EAN
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7KX4
| Anti-CCHFV ADI-36121 Fab | Descriptor: | ADI-36121 Fab heavy chain, ADI-36121 Fab light chain | Authors: | Mishra, A.K, McLellan, J.S. | Deposit date: | 2020-12-03 | Release date: | 2021-12-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375, 2022
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7LVW
| Structure of RSV F in Complex with VHH Cl184 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, F-VHH-Cl184, ... | Authors: | Hsieh, C.-L, McLellan, J.S. | Deposit date: | 2021-02-26 | Release date: | 2021-03-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody. J.Virol., 95, 2021
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7LVU
| Structure of RSV F-directed VHH Cl184 | Descriptor: | F-VHH-Cl184 | Authors: | Hsieh, C.-L, McLellan, J.S. | Deposit date: | 2021-02-26 | Release date: | 2021-03-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody. J.Virol., 95, 2021
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7L7R
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7M8J
| SARS-CoV-2 S-NTD + Fab CM25 | Descriptor: | CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1 | Authors: | Johnson, N.V, Mclellan, J.S. | Deposit date: | 2021-03-29 | Release date: | 2021-05-19 | Last modified: | 2021-06-16 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes. Science, 372, 2021
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7LUC
| Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B | Descriptor: | 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ... | Authors: | Wrapp, D, McLellan, J.S. | Deposit date: | 2021-02-22 | Release date: | 2021-04-21 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021
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7M22
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7M30
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7M1C
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7LYV
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7LYW
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7LUE
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7LUD
| Crystal structure of Fab ADI-14442 | Descriptor: | ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION | Authors: | Rush, S.A, McLellan, J.S. | Deposit date: | 2021-02-22 | Release date: | 2021-06-16 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021
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7L3N
| SARS-CoV 2 Spike Protein bound to LY-CoV555 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV555 Fab heavy chain, ... | Authors: | Goldsmith, J.A, McLellan, J.S. | Deposit date: | 2020-12-18 | Release date: | 2021-02-03 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection. Biorxiv, 2020
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6APC
| Crystal Structure of Infant Antibody ADI-19425 | Descriptor: | Epididymis luminal protein 214, IGL@ protein, SULFATE ION | Authors: | Gilman, M.S.A, McLellan, J.S. | Deposit date: | 2017-08-17 | Release date: | 2018-03-21 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Immunity, 48, 2018
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