6EAG

CRYSTAL STRUCTURE OF FUSION INHIBITOR JNJ-2408068 IN COMPLEX WITH HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN ESCAPE VARIANT G143S STABILIZED IN THE PREFUSION STATE

Summary for 6EAG

• Entry DOI: 10.2210/pdb6eag/pdb
• Descriptor: Fusion glycoprotein F0, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SULFATE ION, ... (5 entities in total)
• Functional Keywords: class i viral fusion protein, fusion, respiratory syncytial virus, prefusion, viral protein, fusion inhibitor
• Biological source: Human respiratory syncytial virus
• Total number of polymer chains: 1
• Total formula weight: 64192.38

Authors

Battles, M.B.,McLellan, J.S. (deposition date: 2018-08-03, release date: 2019-08-07, Last modification date: 2023-10-11)

• Primary citation: Battles, M.B.,McLellan, J.S.; Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance; To be published,

Experimental method

X-RAY DIFFRACTION (3.302 Å)