6APC

Crystal Structure of Infant Antibody ADI-19425

Summary for 6APC

• Entry DOI: 10.2210/pdb6apc/pdb
• Descriptor: Epididymis luminal protein 214, IGL@ protein, SULFATE ION, ... (4 entities in total)
• Functional Keywords: viral fusion glycoprotein, immunoglobulin, respiratory syncytial virus, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 47029.10

Authors

Gilman, M.S.A.,McLellan, J.S. (deposition date: 2017-08-17, release date: 2018-03-21, Last modification date: 2023-10-04)

• Primary citation: Goodwin, E.,Gilman, M.S.A.,Wrapp, D.,Chen, M.,Ngwuta, J.O.,Moin, S.M.,Bai, P.,Sivasubramanian, A.,Connor, R.I.,Wright, P.F.,Graham, B.S.,McLellan, J.S.,Walker, L.M.; Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.; Immunity, 48:339-349.e5, 2018; PubMed: 29396163; DOI: 10.1016/j.immuni.2018.01.005

Experimental method

X-RAY DIFFRACTION (1.7 Å)