6NFX
 
 | | MBTD1 MBT repeats | | Descriptor: | GLYCEROL, MBT domain-containing protein 1,Enhancer of polycomb homolog 1, SODIUM ION, ... | | Authors: | Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-12-21 | | Release date: | 2019-01-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.
Cell Rep, 30, 2020
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4MSV
 | | Crystal structure of FASL and DcR3 complex | | Descriptor: | GLYCEROL, MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 6, ... | | Authors: | Liu, W, Ramagopal, U.A, Zhan, C, Bonanno, J.B, Bhosle, R.C, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2013-09-18 | | Release date: | 2013-11-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.
Structure, 24, 2016
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6AED
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8GTK
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8GTJ
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6J14
 | | Complex structure of GY-14 and PD-1 | | Descriptor: | GY-14 heavy chain V fragment, GY-14 light chain V fragment, Programmed cell death protein 1 | | Authors: | Chen, D, Tan, S, Whang, H, Zhang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | | Deposit date: | 2018-12-27 | | Release date: | 2019-11-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy.
Iscience, 14, 2019
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7C02
 | | Crystal structure of dimeric MERS-CoV receptor binding domain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Dai, L, Qi, J, Gao, G.F. | | Deposit date: | 2020-04-30 | | Release date: | 2020-07-29 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS.
Cell, 182, 2020
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6J15
 | | Complex structure of GY-5 Fab and PD-1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GY-5 heavy chain Fab, ... | | Authors: | Chen, D, Tan, S, Zhang, H, Wang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | | Deposit date: | 2018-12-27 | | Release date: | 2019-11-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy.
Iscience, 14, 2019
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5GIT
 | | BTB domain of KEAP1 in complex with XX3 | | Descriptor: | Kelch-like ECH-associated protein 1, [(3aS,5R,5aS,6S,8S,8aS,9S,9aR)-9-acetyloxy-8-hydroxy-5,8a-dimethyl-1-methylidene-2-oxo-4,5,5a,6,7,8,9,9a-octahydro-3aH-azuleno[6,5-b]furan-6-yl] acetate | | Authors: | Zhu, L.L, Li, H.L, Wu, F.S, Xiong, R. | | Deposit date: | 2016-06-25 | | Release date: | 2017-06-28 | | Last modified: | 2019-01-23 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Britanin Ameliorates Cerebral Ischemia-Reperfusion Injury by Inducing the Nrf2 Protective Pathway.
Antioxid. Redox Signal., 27, 2017
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6IW2
 | | Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state | | Descriptor: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | | Deposit date: | 2018-12-04 | | Release date: | 2019-02-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
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6IEG
 | | Crystal structure of human MTR4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Exosome RNA helicase MTR4, MAGNESIUM ION | | Authors: | Chen, J.Y, Yun, C.H. | | Deposit date: | 2018-09-14 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
Genes Dev., 33, 2019
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6IW5
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6IVZ
 | | Crystal structure of 5A ScFv complexed with YFV-China sE in postfusion state | | Descriptor: | Envelope protein, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | | Deposit date: | 2018-12-04 | | Release date: | 2019-02-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
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6IW4
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6IW0
 | | Crystal structure of 5A ScFv in complex with YFV-17D sE in postfusion state | | Descriptor: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | | Authors: | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | | Deposit date: | 2018-12-04 | | Release date: | 2019-02-13 | | Last modified: | 2019-02-27 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
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6IW1
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6IEH
 | | Crystal structures of the hMTR4-NRDE2 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... | | Authors: | Chen, J.Y, Yun, C.H. | | Deposit date: | 2018-09-14 | | Release date: | 2019-04-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.892 Å) | | Cite: | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
Genes Dev., 33, 2019
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8HRI
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8HRJ
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6AH3
 | | Cryo-EM structure of yeast Ribonuclease P with pre-tRNA substrate | | Descriptor: | MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, ... | | Authors: | Lan, P, Tan, M, Wu, J, Lei, M. | | Deposit date: | 2018-08-16 | | Release date: | 2018-10-17 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structural insight into precursor tRNA processing by yeast ribonuclease P.
Science, 362, 2018
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6AGB
 | | Cryo-EM structure of yeast Ribonuclease P | | Descriptor: | RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, Ribonuclease P protein subunit RPR2, ... | | Authors: | Lan, P, Tan, M, Wu, J, Lei, M. | | Deposit date: | 2018-08-10 | | Release date: | 2018-10-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structural insight into precursor tRNA processing by yeast ribonuclease P.
Science, 362, 2018
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7LVE
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7LXK
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3K51
 | | Crystal Structure of DcR3-TL1A complex | | Descriptor: | Decoy receptor 3, Tumor necrosis factor ligand superfamily member 15, secreted form | | Authors: | Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. | | Deposit date: | 2009-10-06 | | Release date: | 2010-10-13 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
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6CCG
 | | Crystal structure MBD3 MBD domain in complex with methylated CpG DNA | | Descriptor: | DNA, Methyl-CpG-binding domain protein 3, UNKNOWN ATOM OR ION | | Authors: | Liu, K, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-02-07 | | Release date: | 2018-05-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analyses reveal that MBD3 is a methylated CG binder.
Febs J., 286, 2019
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