5GIT

BTB domain of KEAP1 in complex with XX3

Summary for 5GIT

Entry DOI	10.2210/pdb5git/pdb
Descriptor	Kelch-like ECH-associated protein 1, [(3aS,5R,5aS,6S,8S,8aS,9S,9aR)-9-acetyloxy-8-hydroxy-5,8a-dimethyl-1-methylidene-2-oxo-4,5,5a,6,7,8,9,9a-octahydro-3aH-azuleno[6,5-b]furan-6-yl] acetate (3 entities in total)
Functional Keywords	signaling protein, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	15660.06
Authors	Zhu, L.L.,Li, H.L.,Wu, F.S.,Xiong, R. (deposition date: 2016-06-25, release date: 2017-06-28, Last modification date: 2019-01-23)
Primary citation	Wu, G.Z.,Zhu, L.L.,Yuan, X.,Chen, H.,Xiong, R.,Zhang, S.D.,Cheng, H.,Shen, Y.H.,An, H.Z.,Li, T.J.,Li, H.L.,Zhang, W.D. Britanin Ameliorates Cerebral Ischemia-Reperfusion Injury by Inducing the Nrf2 Protective Pathway. Antioxid. Redox Signal., 27:754-768, 2017 Cited by PubMed: 28186440 DOI: 10.1089/ars.2016.6885 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation