5GIT
BTB domain of KEAP1 in complex with XX3
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue XXT A 201 |
| Chain | Residue |
| A | ARG135 |
| A | LYS150 |
| A | CYS151 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 72 |
| Details | Domain: {"description":"BTB","evidences":[{"source":"PROSITE-ProRule","id":"PRU00037","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Sensor for electrophilic agents","evidences":[{"source":"PubMed","id":"18251510","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29590092","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-nitrosocysteine; alternate","evidences":[{"source":"UniProtKB","id":"Q9Z2X8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Cross-link: {"description":"N5-[4-(S-L-cysteinyl)-5-methyl-1H-imidazol-2-yl]-L-ornithine (Arg-Cys) (interchain with C-151 in KEAP1)","evidences":[{"source":"PubMed","id":"30323285","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"N5-[4-(S-L-cysteinyl)-5-methyl-1H-imidazol-2-yl]-L-ornithine (Cys-Arg) (interchain with R-135 in KEAP1)","evidences":[{"source":"PubMed","id":"30323285","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
