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4KGD
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BU of 4kgd by Molmil
High-resolution crystal structure of pyruvate oxidase from L. plantarum in complex with phosphate
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ...
Authors:Neumann, P, Tittmann, K.
Deposit date:2013-04-29
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Observation of a stable carbene at the active site of a thiamin enzyme.
Nat.Chem.Biol., 9, 2013
4KXX
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BU of 4kxx by Molmil
Human transketolase in covalent complex with donor ketose D-sedoheptulose-7-phosphate
Descriptor: (2R,3R,4S,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl dihydrogen phosphate, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Neumann, P, Luedtke, S, Ficner, R, Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
4KXU
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BU of 4kxu by Molmil
Human transketolase in covalent complex with donor ketose D-fructose-6-phosphate
Descriptor: 1,2-ETHANEDIOL, D-SORBITOL-6-PHOSPHATE, MAGNESIUM ION, ...
Authors:Neumann, P, Luedtke, S, Ficner, R, Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
4JQ9
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BU of 4jq9 by Molmil
Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex
Descriptor: CHLORIDE ION, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tietzel, M, Neumann, P, Meyer, D, Ficner, R, Tittmann, K.
Deposit date:2013-03-20
Release date:2014-04-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex
TO BE PUBLISHED
1DIP
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BU of 1dip by Molmil
THE SOLUTION STRUCTURE OF PORCINE DELTA-SLEEP-INDUCING PEPTIDE IMMUNOREACTIVE PEPTIDE, NMR, 10 STRUCTURES
Descriptor: DELTA-SLEEP-INDUCING PEPTIDE IMMUNOREACTIVE PEPTIDE
Authors:Roesch, P, Seidel, G, Adermann, K, Schindler, T, Ejchart, A, Jaenicke, R, Forssmann, W.G.
Deposit date:1997-04-09
Release date:1997-10-15
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of porcine delta sleep-inducing peptide immunoreactive peptide A homolog of the shortsighted gene product.
J.Biol.Chem., 272, 1997
6Y4D
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BU of 6y4d by Molmil
Crystal structure of a short-chain dehydrogenase/reductase (SDR) from Zephyranthes treatiae in complex with NADP+
Descriptor: GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, short-chain dehydrogenase/reductase (SDR)
Authors:Sautner, V, Steimle, S, Roth, S, Mueller, M, Tittmann, K.
Deposit date:2020-02-20
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crossing the Border: From Keto- to Imine Reduction in Short-Chain Dehydrogenases/Reductases.
Chembiochem, 21, 2020
6YJY
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BU of 6yjy by Molmil
Crystal structure of human glutaminyl cyclase in complex with neurotensin 1-5
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTAMINE, Glutaminyl-peptide cyclotransferase, ...
Authors:Funk, L.M, Sautner, V, Tittmann, K.
Deposit date:2020-04-05
Release date:2020-07-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease.
Biochemistry, 59, 2020
6YI1
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BU of 6yi1 by Molmil
Crystal structure of human glutaminyl cyclase in complex with Glu(gamma-hydrazide)-Phe-Ala
Descriptor: 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Kupski, O, Sautner, V, Tittmann, K.
Deposit date:2020-03-31
Release date:2020-07-01
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease.
Biochemistry, 59, 2020
3IO1
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BU of 3io1 by Molmil
Crystal Structure of Aminobenzoyl-glutamate utilization protein from Klebsiella pneumoniae
Descriptor: Aminobenzoyl-glutamate utilization protein, SODIUM ION, YTTRIUM (III) ION
Authors:Kumaran, D, Baumann, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2009-08-13
Release date:2009-08-25
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Aminobenzoyl-glutamate utilization protein from Klebsiella pneumoniae
To be Published
6YR3
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BU of 6yr3 by Molmil
1.48 Angstrom Resolution Crystal Structure of Transaldolase from Thermoplasma acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Descriptor: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
Authors:Sautner, V, Tittmann, K.
Deposit date:2020-04-19
Release date:2021-04-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YRH
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BU of 6yrh by Molmil
Transaldolase variant T30C/D211C from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Descriptor: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
Authors:Sautner, V, Lietzow, T.H, Tittmann, K.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YRT
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BU of 6yrt by Molmil
Transaldolase variant T30D from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Descriptor: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
Authors:Sautner, V, Klaus, M, Tittmann, K.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YS0
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BU of 6ys0 by Molmil
Transaldolase variant D211A from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Descriptor: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
Authors:Sautner, V, Klaus, M, Tittmann, K.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YRE
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BU of 6yre by Molmil
Transaldolase variant T30C/D211C from T. acidophilum
Descriptor: ACETATE ION, GLYCEROL, Probable transaldolase
Authors:Sautner, V, Lietzow, T.H, Tittmann, K.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6YRM
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BU of 6yrm by Molmil
Transaldolase variant T30A from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Descriptor: ACETATE ION, FRUCTOSE -6-PHOSPHATE, GLYCEROL, ...
Authors:Sautner, V, Klaus, M, Tittmann, K.
Deposit date:2020-04-20
Release date:2021-05-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release
To Be Published
6QL5
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BU of 6ql5 by Molmil
Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 2.8 angstrom
Descriptor: 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ...
Authors:Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2020-04-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL7
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BU of 6ql7 by Molmil
Structure of fatty acid synthase complex with bound gamma subunit from Saccharomyces cerevisiae at 4.6 angstrom
Descriptor: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Translation machinery-associated protein 17
Authors:Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL9
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BU of 6ql9 by Molmil
Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom
Descriptor: 1,2-ETHANEDIOL, 4'-PHOSPHOPANTETHEINE, ACETATE ION, ...
Authors:Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
6QL6
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BU of 6ql6 by Molmil
Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom
Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ...
Authors:Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A.
Deposit date:2019-01-31
Release date:2020-03-18
Last modified:2020-04-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 180, 2020
1UYA
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BU of 1uya by Molmil
THE SOLUTION STRUCTURE OF THE A-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES
Descriptor: UROGUANYLIN-16, ISOMER A
Authors:Marx, U.C, Adermann, K, Forssmann, W.-G, Roesch, P.
Deposit date:1997-09-11
Release date:1998-03-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers.
J.Pept.Res., 52, 1998
1UYB
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BU of 1uyb by Molmil
THE SOLUTION STRUCTURE OF THE B-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES
Descriptor: UROGUANYLIN-16, ISOMER B
Authors:Marx, U.C, Adermann, K, Forssmann, W.-G, Roesch, P.
Deposit date:1997-09-11
Release date:1998-03-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers.
J.Pept.Res., 52, 1998
1HPY
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BU of 1hpy by Molmil
THE SOLUTION STRUCTURE OF HUMAN PARATHYROID HORMONE FRAGMENT 1-34 IN 20% TRIFLUORETHANOL, NMR, 10 STRUCTURES
Descriptor: PARATHYROID HORMONE
Authors:Marx, U.C, Roesch, P, Adermann, K, Bayer, P, Forssmann, W.-G.
Deposit date:1998-09-30
Release date:2000-01-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37).
Biochem.Biophys.Res.Commun., 267, 2000
6RJC
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BU of 6rjc by Molmil
E.coli transketolase apoenzyme
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ...
Authors:Rabe von Pappenheim, F, Tittmann, K.
Deposit date:2019-04-26
Release date:2019-09-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
6RJB
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BU of 6rjb by Molmil
Human transketolase variant T382E
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Rabe von Pappenheim, F, Tittmann, K.
Deposit date:2019-04-26
Release date:2019-09-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
8PZ3
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BU of 8pz3 by Molmil
TssM - A USP-like DUB from B. pseudomallei (193-430)
Descriptor: TssM
Authors:Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U.
Deposit date:2023-07-26
Release date:2023-12-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The structural basis for deubiquitination by the fingerless USP-type effector TssM.
Life Sci Alliance, 7, 2024

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