6Y4D

Crystal structure of a short-chain dehydrogenase/reductase (SDR) from Zephyranthes treatiae in complex with NADP+

Summary for 6Y4D

• Entry DOI: 10.2210/pdb6y4d/pdb
• Descriptor: short-chain dehydrogenase/reductase (SDR), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: asymmetric reduction, biocatalysis, imine reduction, mutagenesis, rational design, short-chain dehydrogenase/reductase, zephyranthes treatiae, complex, oxidoreductase
• Biological source: Zephyranthes treatiae
• Total number of polymer chains: 2
• Total formula weight: 63931.54

Authors

Sautner, V.,Steimle, S.,Roth, S.,Mueller, M.,Tittmann, K. (deposition date: 2020-02-20, release date: 2020-04-29, Last modification date: 2024-01-24)

• Primary citation: Roth, S.,Stockinger, P.,Steff, J.,Steimle, S.,Sautner, V.,Tittmann, K.,Pleiss, J.,Muller, M.; Crossing the Border: From Keto- to Imine Reduction in Short-Chain Dehydrogenases/Reductases.; Chembiochem, 21:2615-2619, 2020; PubMed: 32315494; DOI: 10.1002/cbic.202000233

Experimental method

X-RAY DIFFRACTION (2.1 Å)