6YRE

Transaldolase variant T30C/D211C from T. acidophilum

Summary for 6YRE

• Entry DOI: 10.2210/pdb6yre/pdb
• Related: 6YR3
• Descriptor: Probable transaldolase, GLYCEROL, ACETATE ION, ... (4 entities in total)
• Functional Keywords: alpha-beta barrel, conformational selection, domain swapping, transferase, tim barrel, schiff base, large-scale motions, substrate binding, rate-determining product release
• Biological source: Thermoplasma acidophilum DSM 1728
• Total number of polymer chains: 5
• Total formula weight: 123270.98

Authors

Sautner, V.,Lietzow, T.H.,Tittmann, K. (deposition date: 2020-04-20, release date: 2021-05-12, Last modification date: 2024-01-24)

• Primary citation: Sautner, V.,Lietzow, T.H.,Klaus, M.,Funk, L.M.,Tittmann, K.; Large-scale motions underlie physical but not chemical steps in transaldolase mechanism: Substrate binding by conformational selection and rate-determining product release; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.96 Å)