Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6YRE

Transaldolase variant T30C/D211C from T. acidophilum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004801	molecular_function	transaldolase activity
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006098	biological_process	pentose-phosphate shunt
A	0016740	molecular_function	transferase activity
A	0016832	molecular_function	aldehyde-lyase activity
B	0004801	molecular_function	transaldolase activity
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0006098	biological_process	pentose-phosphate shunt
B	0016740	molecular_function	transferase activity
B	0016832	molecular_function	aldehyde-lyase activity
C	0004801	molecular_function	transaldolase activity
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0006098	biological_process	pentose-phosphate shunt
C	0016740	molecular_function	transferase activity
C	0016832	molecular_function	aldehyde-lyase activity
D	0004801	molecular_function	transaldolase activity
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0006098	biological_process	pentose-phosphate shunt
D	0016740	molecular_function	transferase activity
D	0016832	molecular_function	aldehyde-lyase activity
E	0004801	molecular_function	transaldolase activity
E	0005737	cellular_component	cytoplasm
E	0005975	biological_process	carbohydrate metabolic process
E	0006098	biological_process	pentose-phosphate shunt
E	0016740	molecular_function	transferase activity
E	0016832	molecular_function	aldehyde-lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue ACT A 302

Chain	Residue
A	MET1
A	HOH414
E	LEU119
E	LYS123
E	TYR157
E	ILE159

site_id	AC2
Number of Residues	7
Details	binding site for residue ACT B 302

Chain	Residue
B	HOH417
B	HOH446
D	ARG169
D	ASN170
B	ARG169
B	ASN170
B	HOH406

site_id	AC3
Number of Residues	5
Details	binding site for residue GOL C 301

Chain	Residue
C	ASP142
C	GLN145
C	ARG176
C	HOH405
C	HOH455

site_id	AC4
Number of Residues	10
Details	binding site for residue GOL C 302

Chain	Residue
C	ASP137
C	ASN170
C	ASN170
C	ILE172
C	ILE172
C	HIS173
C	HIS173
C	ARG176
C	ARG176
C	HOH410

site_id	AC5
Number of Residues	8
Details	binding site for residue ACT C 303

Chain	Residue
C	ARG169
C	ARG169
C	ASN170
C	ASN170
C	HOH411
C	HOH411
C	HOH450
C	HOH450

site_id	AC6
Number of Residues	7
Details	binding site for residue ACT E 302

Chain	Residue
A	ARG169
A	ASN170
E	ARG169
E	ASN170
E	HOH401
E	HOH407
E	HOH441

site_id	AC7
Number of Residues	1
Details	binding site for residue ACT E 303

Chain	Residue
E	ARG176

site_id	AC8
Number of Residues	20
Details	binding site for residues GOL A 301 and GOL E 301

Chain	Residue
A	ASP137
A	ASN170
A	ASN170
A	ILE172
A	HIS173
A	HIS173
A	ARG176
A	ARG176
A	HOH419
A	HOH419
E	ASP137
E	ASN170
E	ILE172
E	ILE172
E	HIS173
E	HIS173
E	ARG176
E	ARG176
E	HOH422
E	HOH422

site_id	AC9
Number of Residues	20
Details	binding site for residues GOL A 301 and GOL E 301

Chain	Residue
A	ASP137
A	ASN170
A	ASN170
A	ILE172
A	HIS173
A	HIS173
A	ARG176
A	ARG176
A	HOH419
A	HOH419
E	ASP137
E	ASN170
E	ILE172
E	ILE172
E	HIS173
E	HIS173
E	ARG176
E	ARG176
E	HOH422
E	HOH422

site_id	AD1
Number of Residues	20
Details	binding site for residues GOL A 301 and GOL E 301

Chain	Residue
E	HIS173
E	ARG176
E	ARG176
E	HOH422
E	HOH422
A	ASP137
A	ASN170
A	ASN170
A	ILE172
A	HIS173
A	HIS173
A	ARG176
A	ARG176
A	HOH419
A	HOH419
E	ASP137
E	ASN170
E	ILE172
E	ILE172
E	HIS173

site_id	AD2
Number of Residues	20
Details	binding site for residues GOL A 301 and GOL E 301

Chain	Residue
A	ASP137
A	ASN170
A	ASN170
A	ILE172
A	HIS173
A	HIS173
A	ARG176
A	ARG176
A	HOH419
A	HOH419
E	ASP137
E	ASN170
E	ILE172
E	ILE172
E	HIS173
E	HIS173
E	ARG176
E	ARG176
E	HOH422
E	HOH422

site_id	AD3
Number of Residues	20
Details	binding site for residues GOL A 301 and GOL E 301

Chain	Residue
A	ASP137
A	ASN170
A	ASN170
A	ILE172
A	HIS173
A	HIS173
A	ARG176
A	ARG176
A	HOH419
A	HOH419
E	ASP137
E	ASN170
E	ILE172
E	ILE172
E	HIS173
E	HIS173
E	ARG176
E	ARG176
E	HOH422
E	HOH422

site_id	AD4
Number of Residues	20
Details	binding site for residues GOL A 301 and GOL E 301

Chain	Residue
A	ASP137
A	ASN170
A	ASN170
A	ILE172
A	HIS173
A	HIS173
A	ARG176
A	ARG176
A	HOH419
A	HOH419
E	ASP137
E	ASN170
E	ILE172
E	ILE172
E	HIS173
E	HIS173
E	ARG176
E	ARG176
E	HOH422
E	HOH422

site_id	AD5
Number of Residues	20
Details	binding site for residues GOL A 301 and GOL E 301

Chain	Residue
A	ASP137
A	ASN170
A	ASN170
A	ILE172
A	HIS173
A	HIS173
A	ARG176
A	ARG176
A	HOH419
A	HOH419
E	ASP137
E	ASN170
E	ILE172
E	ILE172
E	HIS173
E	HIS173
E	ARG176
E	ARG176
E	HOH422
E	HOH422

site_id	AD6
Number of Residues	20
Details	binding site for residues GOL A 301 and GOL E 301

Chain	Residue
A	ASP137
A	ASN170
A	ASN170
A	ILE172
A	HIS173
A	HIS173
A	ARG176
A	ARG176
A	HOH419
A	HOH419
E	ASP137
E	ASN170
E	ILE172
E	ILE172
E	HIS173
E	HIS173
E	ARG176
E	ARG176
E	HOH422
E	HOH422

site_id	AD7
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AD8
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AD9
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AE1
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AE2
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AE3
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AE4
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AE5
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AE6
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

site_id	AE7
Number of Residues	21
Details	binding site for residues GOL B 301 and GOL D 301

Chain	Residue
B	ASP137
B	ASN170
B	ASN170
B	ILE172
B	HIS173
B	HIS173
B	ARG176
B	ARG176
B	HOH405
B	HOH405
D	ASP137
D	ASN170
D	ASN170
D	ILE172
D	ILE172
D	HIS173
D	HIS173
D	ARG176
D	ARG176
D	HOH414
D	HOH414

Functional Information from PROSITE/UniProt

site_id	PS00958
Number of Residues	18
Details	TRANSALDOLASE_2 Transaldolase active site. AvVKIPmTeDGLrAiKtL

Chain	Residue	Details
A	ALA83-LEU100

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000250

Chain	Residue	Details
A	LYS86
B	LYS86
C	LYS86
D	LYS86
E	LYS86

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)