6QL9

Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom

This is a large structure.

Summary for 6QL9

DescriptorFatty acid synthase subunit alpha, Fatty acid synthase subunit beta, 4'-PHOSPHOPANTETHEINE, ... (12 entities in total)
Functional Keywordsfatty acid synthase, acyl carrier protein, ketosynthase, ketoreductase, enoyl reductase, dehydratase, malonyl/palmitoyl transferase, acetyl transferase, phosphopantetheine transferase, transferase
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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Total number of polymer chains12
Total molecular weight2630307.96
Authors
Singh, K.,Graf, B.,Linden, A.,Sautner, V.,Urlaub, H.,Tittmann, K.,Stark, H.,Chari, A. (deposition date: 2019-01-31, release date: 2020-03-18, Last modification date: 2020-03-25)
Primary citation
Singh, K.,Graf, B.,Linden, A.,Sautner, V.,Urlaub, H.,Tittmann, K.,Stark, H.,Chari, A.
Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 2020
PubMed: 32160528 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2020.02.034
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.82 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2117 0.6% 12.5% 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload