1W3R
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![BU of 1w3r by Molmil](/molmil-images/mine/1w3r) | NimA from D. radiodurans with Metronidazole and Pyruvate | Descriptor: | ACETATE ION, Metronidazole, NIMA-RELATED PROTEIN, ... | Authors: | Leiros, H.-K.S, Kozielski-Stuhrmann, S, Kapp, U, Terradot, L, Leonard, G.A, McSweeney, S.M. | Deposit date: | 2004-07-17 | Release date: | 2004-10-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis of 5-Nitroimidazole Antibiotic Resistance: The Crystal Structure of Nima from Deinococcus Radiodurans J.Biol.Chem., 279, 2004
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1W3Q
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![BU of 1w3q by Molmil](/molmil-images/mine/1w3q) | NimA from D. radiodurans with covalenly bound lactate | Descriptor: | ACETATE ION, LACTIC ACID, NIMA-RELATED PROTEIN | Authors: | Leiros, H.-K.S, Kozielski-Stuhrmann, S, Kapp, U, Terradot, L, Leonard, G.A, Mcsweeney, S.M. | Deposit date: | 2004-07-17 | Release date: | 2004-10-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structural Basis of 5-Nitroimidazole Antibiotic Resistance: The Crystal Structure of Nima from Deinococcus Radiodurans J.Biol.Chem., 279, 2004
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1W3O
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![BU of 1w3o by Molmil](/molmil-images/mine/1w3o) | Crystal structure of NimA from D. radiodurans | Descriptor: | ACETATE ION, NIMA-RELATED PROTEIN, PYRUVIC ACID | Authors: | Leiros, H.-K.S, Kozielski-Stuhrmann, S, Kapp, U, Terradot, L, Leonard, G.A, McSweeney, S.M. | Deposit date: | 2004-07-17 | Release date: | 2004-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis of 5-Nitroimidazole Antibiotic Resistance: The Crystal Structure of Nima from Deinococcus Radiodurans J.Biol.Chem., 279, 2004
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1MLZ
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![BU of 1mlz by Molmil](/molmil-images/mine/1mlz) | Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the trans-isomer of amiclenomycin. | Descriptor: | 7,8-diamino-pelargonic acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... | Authors: | Sandmark, J, Mann, S, Marquet, A, Schneider, G. | Deposit date: | 2002-09-02 | Release date: | 2002-12-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin J.Biol.Chem., 277, 2002
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1EXB
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![BU of 1exb by Molmil](/molmil-images/mine/1exb) | STRUCTURE OF THE CYTOPLASMIC BETA SUBUNIT-T1 ASSEMBLY OF VOLTAGE-DEPENDENT K CHANNELS | Descriptor: | KV BETA2 PROTEIN, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM CHANNEL KV1.1 | Authors: | Gulbis, J.M, Zhou, M, Mann, S, MacKinnon, R. | Deposit date: | 2000-05-02 | Release date: | 2000-07-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels. Science, 289, 2000
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1VPU
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![BU of 1vpu by Molmil](/molmil-images/mine/1vpu) | |
5CVS
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![BU of 5cvs by Molmil](/molmil-images/mine/5cvs) | GlgE isoform 1 from Streptomyces coelicolor E423A mutant soaked in maltoheptaose | Descriptor: | Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Rashid, A.M, Syson, K, Koliwer-Brandl, H, van de Weerd, R, Stevenson, C.E.M, Batey, S.F.D, Miah, F, Alber, M, Ioerger, T.R, Chandra, G, Appelmelk, B.J, Nartowski, K.P, Khimyak, Y.Z, Lawson, D.M, Jacobs, W.R, Geurtsen, J, Kalscheuer, R, Bornemann, S. | Deposit date: | 2015-07-27 | Release date: | 2016-08-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Ligand-bound structures and site-directed mutagenesis identify the acceptor and secondary binding sites of Streptomyces coelicolor maltosyltransferase GlgE. J.Biol.Chem., 291, 2016
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1W1F
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![BU of 1w1f by Molmil](/molmil-images/mine/1w1f) | SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE | Descriptor: | TYROSINE-PROTEIN KINASE LYN | Authors: | Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H. | Deposit date: | 2004-06-17 | Release date: | 2005-07-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Characterization of Lyn-SH3 Domain in Complex with a Herpesviral Protein Reveals an Extended Recognition Motif that Enhances Binding Affinity. Protein Sci., 14, 2005
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2G32
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![BU of 2g32 by Molmil](/molmil-images/mine/2g32) | Crystal structure of an RNA racemate | Descriptor: | CALCIUM ION, GLYCEROL, RNA (5'-R(*(0C)P*(0C)P*(0G)P*(0C)P*(0C)P*(0U)P*(0G)P*(0G))-3'), ... | Authors: | Rypniewski, W, Vallazza, M, Perbandt, M, Klussmann, S, Betzel, C, Erdmann, V.A. | Deposit date: | 2006-02-17 | Release date: | 2006-05-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The first crystal structure of an RNA racemate. Acta Crystallogr.,Sect.D, 62, 2006
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1WA7
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![BU of 1wa7 by Molmil](/molmil-images/mine/1wa7) | SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND | Descriptor: | HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1), TYROSINE-PROTEIN KINASE LYN | Authors: | Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H. | Deposit date: | 2004-10-25 | Release date: | 2005-07-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck. Biochemistry, 41, 2002
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4WB3
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![BU of 4wb3 by Molmil](/molmil-images/mine/4wb3) | Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a-desArg complement anaphylatoxin | Descriptor: | ACETATE ION, CALCIUM ION, Complement C5, ... | Authors: | Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R. | Deposit date: | 2014-09-02 | Release date: | 2015-05-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer. Nat Commun, 6, 2015
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4WB2
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![BU of 4wb2 by Molmil](/molmil-images/mine/4wb2) | Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a complement anaphylatoxin | Descriptor: | ACETATE ION, CALCIUM ION, Complement C5, ... | Authors: | Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R. | Deposit date: | 2014-09-02 | Release date: | 2015-05-06 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer. Nat Commun, 6, 2015
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5K6X
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![BU of 5k6x by Molmil](/molmil-images/mine/5k6x) | Sidekick-2 immunoglobulin domains 1-4, crystal form 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. | Deposit date: | 2016-05-25 | Release date: | 2016-09-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular basis of sidekick-mediated cell-cell adhesion and specificity. Elife, 5, 2016
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5K6Y
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![BU of 5k6y by Molmil](/molmil-images/mine/5k6y) | Sidekick-2 immunoglobulin domains 1-4, crystal form 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Protein sidekick-2 | Authors: | Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. | Deposit date: | 2016-05-25 | Release date: | 2016-09-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Molecular basis of sidekick-mediated cell-cell adhesion and specificity. Elife, 5, 2016
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3PCQ
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![BU of 3pcq by Molmil](/molmil-images/mine/3pcq) | Femtosecond X-ray protein Nanocrystallography | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | Authors: | Chapman, H.N, Fromme, P, Barty, A, White, T.A, Kirian, R.A, Aquila, A, Hunter, M.S, Schulz, J, Deponte, D.P, Weierstall, U, Doak, R.B, Maia, F.R.N.C, Martin, A.V, Schlichting, I, Lomb, L, Coppola, N, Shoeman, R.L, Epp, S.W, Hartmann, R, Rolles, D, Rudenko, A, Foucar, L, Kimmel, N, Weidenspointner, G, Holl, P, Liang, M, Barthelmess, M, Caleman, C, Boutet, S, Bogan, M.J, Krzywinski, J, Bostedt, C, Bajt, S, Gumprecht, L, Rudek, B, Erk, B, Schmidt, C, Homke, A, Reich, C, Pietschner, D, Struder, L, Hauser, G, Gorke, H, Ullrich, J, Herrmann, S, Schaller, G, Schopper, F, Soltau, H, Kuhnel, K.-U, Messerschmidt, M, Bozek, J.D, Hau-Riege, S.P, Frank, M, Hampton, C.Y, Sierra, R, Starodub, D, Williams, G.J, Hajdu, J, Timneanu, N, Seibert, M.M, Andreasson, J, Rocker, A, Jonsson, O, Svenda, M, Stern, S, Nass, K, Andritschke, R, Schroter, C.-D, Krasniqi, F, Bott, M, Schmidt, K.E, Wang, X, Grotjohann, I, Holton, J.M, Barends, T.R.M, Neutze, R, Marchesini, S, Fromme, R, Schorb, S, Rupp, D, Adolph, M, Gorkhover, T, Andersson, I, Hirsemann, H, Potdevin, G, Graafsma, H, Nilsson, B, Spence, J.C.H. | Deposit date: | 2010-10-21 | Release date: | 2011-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (8.984 Å) | Cite: | Femtosecond X-ray protein nanocrystallography. Nature, 470, 2011
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5DGS
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![BU of 5dgs by Molmil](/molmil-images/mine/5dgs) | |
1PVW
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![BU of 1pvw by Molmil](/molmil-images/mine/1pvw) | 3,4-dihydroxy-2-butanone 4-phosphate synthase from M. jannaschii | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Steinbacher, S, Schiffmann, S, Richter, G, Huber, R, Bacher, A, Fischer, M. | Deposit date: | 2003-06-29 | Release date: | 2003-11-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of 3,4-Dihydroxy-2-butanone 4-Phosphate Synthase from Methanococcus jannaschii in
Complex with Divalent Metal Ions and the Substrate Ribulose 5-Phosphate: IMPLICATIONS FOR THE
CATALYTIC MECHANISM J.Biol.Chem., 278, 2003
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1PVY
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![BU of 1pvy by Molmil](/molmil-images/mine/1pvy) | 3,4-dihydroxy-2-butanone 4-phosphate synthase from M. jannaschii in complex with ribulose 5-phosphate | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, CALCIUM ION, RIBULOSE-5-PHOSPHATE, ... | Authors: | Steinbacher, S, Schiffmann, S, Richter, G, Huber, R, Bacher, A, Fischer, M. | Deposit date: | 2003-06-29 | Release date: | 2003-11-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of 3,4-Dihydroxy-2-butanone 4-Phosphate Synthase from Methanococcus jannaschii in
Complex with Divalent Metal Ions and the Substrate Ribulose 5-Phosphate: IMPLICATIONS FOR THE
CATALYTIC MECHANISM J.Biol.Chem., 278, 2003
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2MUS
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![BU of 2mus by Molmil](/molmil-images/mine/2mus) | HADDOCK calculated model of LIN5001 bound to the HET-s amyloid | Descriptor: | 3''',4'-bis(carboxymethyl)-2,2':5',2'':5'',2''':5''',2''''-quinquethiophene-5,5''''-dicarboxylic acid, Heterokaryon incompatibility protein s | Authors: | Hermann, U.S, Schuetz, A.K, Shirani, H, Saban, D, Nuvolone, M, Huang, D.H, Li, B, Ballmer, B, Aslund, A.K.O, Mason, J.J, Rushing, E, Budka, H, Hammarstrom, P, Bockmann, A, Caflisch, A, Meier, B.H, Nilsson, P.K.R, Hornemann, S, Aguzzi, A. | Deposit date: | 2014-09-16 | Release date: | 2017-02-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure-based drug design identifies polythiophenes as antiprion compounds. Sci Transl Med, 7, 2015
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2JNR
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![BU of 2jnr by Molmil](/molmil-images/mine/2jnr) | Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide | Descriptor: | ENV polyprotein, VIR165 | Authors: | Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F. | Deposit date: | 2007-02-01 | Release date: | 2007-05-08 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide. Cell(Cambridge,Mass.), 129, 2007
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3I5R
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![BU of 3i5r by Molmil](/molmil-images/mine/3i5r) | PI3K SH3 domain in complex with a peptide ligand | Descriptor: | Peptide ligand, Phosphatidylinositol 3-kinase regulatory subunit alpha | Authors: | Batra-Safferling, R, Granzin, J, Modder, S, Hoffmann, S, Willbold, D. | Deposit date: | 2009-07-06 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural studies of the phosphatidylinositol 3-kinase (PI3K) SH3 domain in complex with a peptide ligand: role of the anchor residue in ligand binding. Biol.Chem., 391, 2010
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3I5S
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![BU of 3i5s by Molmil](/molmil-images/mine/3i5s) | Crystal structure of PI3K SH3 | Descriptor: | Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION | Authors: | Batra-Safferling, R, Granzin, J, Modder, S, Hoffmann, S, Willbold, D. | Deposit date: | 2009-07-06 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural studies of the phosphatidylinositol 3-kinase (PI3K) SH3 domain in complex with a peptide ligand: role of the anchor residue in ligand binding. Biol.Chem., 391, 2010
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6ZTB
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![BU of 6ztb by Molmil](/molmil-images/mine/6ztb) | Crystal Structure of human P-Cadherin EC1_EC2 | Descriptor: | CALCIUM ION, Cadherin-3, SODIUM ION | Authors: | Rondeau, J.M, Lehmann, S. | Deposit date: | 2020-07-17 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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6ZTF
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![BU of 6ztf by Molmil](/molmil-images/mine/6ztf) | Crystal Structure of the anti-human P-Cadherin Fab CQY684 | Descriptor: | CQY684 Fab heavy-chain, CQY684 Fab light-chain | Authors: | Rondeau, J.M, Lehmann, S. | Deposit date: | 2020-07-20 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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6ZTR
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![BU of 6ztr by Molmil](/molmil-images/mine/6ztr) | Crystal Structure of the anti-human P-Cadherin Fab CQY684 in complex with human P-Cadherin(108-324) | Descriptor: | CALCIUM ION, CQY684 Fab heavy-chain, CQY684 Fab light-chain, ... | Authors: | Rondeau, J.M, Lehmann, S. | Deposit date: | 2020-07-20 | Release date: | 2021-05-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies. Mol.Cancer Ther., 20, 2021
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