1WA7

SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE IN COMPLEX WITH A HERPESVIRAL LIGAND

Summary for 1WA7

• Entry DOI: 10.2210/pdb1wa7/pdb
• Related: 1W1F
• NMR Information: BMRB: 6456
• Descriptor: TYROSINE-PROTEIN KINASE LYN, HYPOTHETICAL 28.7 KDA PROTEIN IN DHFR 3'REGION (ORF1) (2 entities in total)
• Functional Keywords: sh3 domain, ligand, tyrosine kinase, signal transduction, lyn, tip, proto-oncogene, hypothetical protein
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cell membrane: P07948; Host cell membrane; Single-pass membrane protein (By similarity): P22575
• Total number of polymer chains: 2
• Total formula weight: 9774.08

Authors

Bauer, F.,Schweimer, K.,Hoffmann, S.,Roesch, P.,Sticht, H. (deposition date: 2004-10-25, release date: 2005-07-07, Last modification date: 2011-07-13)

• Primary citation: Schweimer, K.,Hoffmann, S.,Bauer, F.,Friedrich, U.,Kardinal, C.,Feller, S.M.,Biesinger, B.,Sticht, H.; Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck.; Biochemistry, 41:5120-, 2002; PubMed: 11955060; DOI: 10.1021/BI015986J

Experimental method

SOLUTION NMR