1W3R

NimA from D. radiodurans with Metronidazole and Pyruvate

Summary for 1W3R

• Entry DOI: 10.2210/pdb1w3r/pdb
• Related: 1W3O 1W3P 1W3Q
• Descriptor: NIMA-RELATED PROTEIN, ACETATE ION, PYRUVIC ACID, ... (5 entities in total)
• Functional Keywords: antibiotic resistance, deinococcus radiodurans, 5-nitroimidazole resistance, nim gene, catalytic mechanism
• Biological source: DEINOCOCCUS RADIODURANS
• Total number of polymer chains: 1
• Total formula weight: 24785.49

Authors

Leiros, H.-K.S.,Kozielski-Stuhrmann, S.,Kapp, U.,Terradot, L.,Leonard, G.A.,McSweeney, S.M. (deposition date: 2004-07-17, release date: 2004-10-18, Last modification date: 2023-12-13)

• Primary citation: Leiros, H.-K.S.,Kozielski-Stuhrmann, S.,Kapp, U.,Terradot, L.,Leonard, G.A.,Mcsweeney, S.M.; Structural Basis of 5-Nitroimidazole Antibiotic Resistance: The Crystal Structure of Nima from Deinococcus Radiodurans; J.Biol.Chem., 279:55840-, 2004; PubMed: 15492014; DOI: 10.1074/JBC.M408044200

Experimental method

X-RAY DIFFRACTION (1.9 Å)