6CKH
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![BU of 6ckh by Molmil](/molmil-images/mine/6ckh) | Manduca sexta Peptidoglycan Recognition Protein-1 | Descriptor: | Peptidoglycan-recognition protein | Authors: | Hu, Y. | Deposit date: | 2018-02-28 | Release date: | 2019-06-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The three-dimensional structure and recognition mechanism of Manduca sexta peptidoglycan recognition protein-1. Insect Biochem.Mol.Biol., 108, 2019
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6UI4
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![BU of 6ui4 by Molmil](/molmil-images/mine/6ui4) | Crystal structure of phenamacril-bound F. graminearum myosin I | Descriptor: | Calmodulin, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, Y, Zhou, X.E, Gong, Y, Zhu, Y, Xu, H.E, Zhou, M, Melcher, K, Zhang, F. | Deposit date: | 2019-09-30 | Release date: | 2020-03-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis of Fusarium myosin I inhibition by phenamacril. Plos Pathog., 16, 2020
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8G05
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![BU of 8g05 by Molmil](/molmil-images/mine/8g05) | Cryo-EM structure of an orphan GPCR-Gi protein signaling complex | Descriptor: | 6-(octylamino)pyrimidine-2,4(3H,5H)-dione, CHOLESTEROL, G-protein coupled receptor 84, ... | Authors: | Zhang, X, Wang, Y.J, Li, X, Liu, G.B, Gong, W.M, Zhang, C. | Deposit date: | 2023-01-31 | Release date: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Pro-phagocytic function and structural basis of GPR84 signaling. Nat Commun, 14, 2023
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4RZH
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![BU of 4rzh by Molmil](/molmil-images/mine/4rzh) | Crystal structure of FabG from Synechocystis sp. PCC 6803 | Descriptor: | 3-oxoacyl-[acyl-carrier protein] reductase | Authors: | Liu, Y, Xue, S. | Deposit date: | 2014-12-22 | Release date: | 2015-09-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-directed construction of a high-performance version of the enzyme FabG from the photosynthetic microorganism Synechocystis sp. PCC 6803. Febs Lett., 589, 2015
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4J53
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![BU of 4j53 by Molmil](/molmil-images/mine/4j53) | Crystal structure of PLK1 in complex with TAK-960 | Descriptor: | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide, ACETATE ION, Serine/threonine-protein kinase PLK1, ... | Authors: | Hosfield, D.J, Skene, R.J. | Deposit date: | 2013-02-07 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1). Bioorg.Med.Chem.Lett., 23, 2013
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4J52
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![BU of 4j52 by Molmil](/molmil-images/mine/4j52) | Crystal structure of PLK1 in complex with a pyrimidodiazepinone inhibitor | Descriptor: | 4-{[(7R)-9-cyclopentyl-7-ethenyl-7-fluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl]amino}-3-methoxy-N-(4-methylpiperazin-1-yl)benzamide, ACETATE ION, Serine/threonine-protein kinase PLK1, ... | Authors: | Hosfield, D.J, Skene, R.J. | Deposit date: | 2013-02-07 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1). Bioorg.Med.Chem.Lett., 23, 2013
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2KCJ
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![BU of 2kcj by Molmil](/molmil-images/mine/2kcj) | solution structure of FAPP1 PH domain | Descriptor: | Pleckstrin homology domain-containing family A member 3 | Authors: | Lenoir, M, Coskun, U, James, J, Simons, K, Overduin, M. | Deposit date: | 2008-12-22 | Release date: | 2009-12-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains. Embo Rep., 11, 2010
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8HIL
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![BU of 8hil by Molmil](/molmil-images/mine/8hil) | A cryo-EM structure of B. oleracea RNA polymerase V at 3.57 Angstrom | Descriptor: | DNA-dependent RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, DNA-directed RNA polymerase subunit, ... | Authors: | Du, X, Xie, G, Hu, H, Du, J. | Deposit date: | 2022-11-20 | Release date: | 2023-03-22 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structure and mechanism of the plant RNA polymerase V. Science, 379, 2023
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8HIM
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![BU of 8him by Molmil](/molmil-images/mine/8him) | A cryo-EM structure of B. oleracea RNA polymerase V elongation complex at 2.73 Angstrom | Descriptor: | DNA (34-MER), DNA-directed RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, ... | Authors: | Hu, H, Xie, G, Du, X, Du, J. | Deposit date: | 2022-11-21 | Release date: | 2023-03-22 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure and mechanism of the plant RNA polymerase V. Science, 379, 2023
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6IP0
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![BU of 6ip0 by Molmil](/molmil-images/mine/6ip0) | |
6IP4
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![BU of 6ip4 by Molmil](/molmil-images/mine/6ip4) | |
7KRN
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![BU of 7krn by Molmil](/molmil-images/mine/7krn) | Structure of SARS-CoV-2 backtracked complex bound to nsp13 helicase - nsp13(1)-BTC | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2020-11-20 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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7KRP
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![BU of 7krp by Molmil](/molmil-images/mine/7krp) | Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - BTC (local refinement) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHAPSO, MAGNESIUM ION, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2020-11-20 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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7KRO
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![BU of 7kro by Molmil](/molmil-images/mine/7kro) | Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - nsp13(2)-BTC | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2020-11-20 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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5YKO
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![BU of 5yko by Molmil](/molmil-images/mine/5yko) | |
5YKN
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![BU of 5ykn by Molmil](/molmil-images/mine/5ykn) | crystal structure of Arabidopsis thaliana JMJ14 catalytic domain | Descriptor: | NICKEL (II) ION, Probable lysine-specific demethylase JMJ14, ZINC ION | Authors: | Yang, Z, Du, J. | Deposit date: | 2017-10-15 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases. Plant Cell, 30, 2018
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8H2J
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![BU of 8h2j by Molmil](/molmil-images/mine/8h2j) | Structure of Acb2 complexed with 3',3'-cGAMP | Descriptor: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, p26 | Authors: | Feng, Y, Cao, X.L. | Deposit date: | 2022-10-06 | Release date: | 2023-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Bacteriophages inhibit and evade cGAS-like immune function in bacteria. Cell, 186, 2023
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8H2X
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![BU of 8h2x by Molmil](/molmil-images/mine/8h2x) | Structure of Acb2 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, p26 | Authors: | Feng, Y, Cao, X.L. | Deposit date: | 2022-10-07 | Release date: | 2023-02-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Bacteriophages inhibit and evade cGAS-like immune function in bacteria. Cell, 186, 2023
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8H39
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![BU of 8h39 by Molmil](/molmil-images/mine/8h39) | Structure of Acb2 complexed with c-di-AMP | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, 1,2-ETHANEDIOL, p26 | Authors: | Feng, Y, Cao, X.L. | Deposit date: | 2022-10-08 | Release date: | 2023-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Bacteriophages inhibit and evade cGAS-like immune function in bacteria. Cell, 186, 2023
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6MFE
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![BU of 6mfe by Molmil](/molmil-images/mine/6mfe) | Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000773 (Compound 11g) Complex | Descriptor: | (2-nitro-4-{[(3S)-1-{[4-(trifluoromethoxy)phenyl]methyl}pyrrolidin-3-yl]amino}phenyl)methanol, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein | Authors: | Taylor, A.B. | Deposit date: | 2018-09-10 | Release date: | 2018-10-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.444 Å) | Cite: | Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents. ACS Med Chem Lett, 9, 2018
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6B52
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![BU of 6b52 by Molmil](/molmil-images/mine/6b52) | |
6BDP
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![BU of 6bdp by Molmil](/molmil-images/mine/6bdp) | Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000071 (Compound 9c) Complex | Descriptor: | (4-{[(3R)-1-benzylpyrrolidin-3-yl]amino}-2-nitrophenyl)methanol, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein | Authors: | Taylor, A.B. | Deposit date: | 2017-10-24 | Release date: | 2018-10-03 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents. ACS Med Chem Lett, 9, 2018
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6BDR
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![BU of 6bdr by Molmil](/molmil-images/mine/6bdr) | Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000206 (Compound 9f) Complex | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein, [4-({(3R)-1-[(1H-indol-3-yl)methyl]pyrrolidin-3-yl}amino)-2-nitrophenyl]methanol | Authors: | Taylor, A.B. | Deposit date: | 2017-10-24 | Release date: | 2018-10-03 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents. ACS Med Chem Lett, 9, 2018
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6B4X
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![BU of 6b4x by Molmil](/molmil-images/mine/6b4x) | Schistosoma mansoni (Blood Fluke) Sulfotransferase, F39Y Mutant | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, ... | Authors: | Taylor, A.B. | Deposit date: | 2017-09-27 | Release date: | 2018-10-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum? Int.J.Parasitol., 2020
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6BDS
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![BU of 6bds by Molmil](/molmil-images/mine/6bds) | Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000204 (Compound 11f) Complex | Descriptor: | (2-nitro-4-{[(3S)-1-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]amino}phenyl)methanol, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein | Authors: | Taylor, A.B. | Deposit date: | 2017-10-24 | Release date: | 2018-10-03 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents. ACS Med Chem Lett, 9, 2018
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