7KRO

Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - nsp13(2)-BTC

Summary for 7KRO

Entry DOI	10.2210/pdb7kro/pdb
EMDB information	23007 23008 23009
Descriptor	RNA-directed RNA polymerase, CHAPSO, ALUMINUM FLUORIDE, ... (11 entities in total)
Functional Keywords	rna-dependent rna polymerase, viral replication-transcription complex, transcription, viral proteins, transferase-hydrolase-rna complex, transferase/hydrolase/rna
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More
Total number of polymer chains	8
Total formula weight	329488.27
Authors	Chen, J.,Malone, B.,Campbell, E.A.,Darst, S.A. (deposition date: 2020-11-20, release date: 2021-04-21, Last modification date: 2024-03-06)
Primary citation	Malone, B.,Chen, J.,Wang, Q.,Llewellyn, E.,Choi, Y.J.,Olinares, P.D.B.,Cao, X.,Hernandez, C.,Eng, E.T.,Chait, B.T.,Shaw, D.E.,Landick, R.,Darst, S.A.,Campbell, E.A. Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33883267 DOI: 10.1073/pnas.2102516118 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation