8G05

Cryo-EM structure of an orphan GPCR-Gi protein signaling complex

Summary for 8G05

Entry DOI	10.2210/pdb8g05/pdb
EMDB information	29645
Descriptor	G-protein coupled receptor 84, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
Functional Keywords	gpcr, agonist, 6-oau, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	167141.46
Authors	Zhang, X.,Wang, Y.J.,Li, X.,Liu, G.B.,Gong, W.M.,Zhang, C. (deposition date: 2023-01-31, release date: 2023-11-01)
Primary citation	Zhang, X.,Wang, Y.,Supekar, S.,Cao, X.,Zhou, J.,Dang, J.,Chen, S.,Jenkins, L.,Marsango, S.,Li, X.,Liu, G.,Milligan, G.,Feng, M.,Fan, H.,Gong, W.,Zhang, C. Pro-phagocytic function and structural basis of GPR84 signaling. Nat Commun, 14:5706-5706, 2023 Cited by PubMed: 37709767 DOI: 10.1038/s41467-023-41201-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation