3ENS
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3FH5
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3FH8
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3FHE
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5GJU
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![BU of 5gju by Molmil](/molmil-images/mine/5gju) | DEAD-box RNA helicase | Descriptor: | ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DeaD | Authors: | Xu, L, Li, F, Wang, L, Shi, Y. | Deposit date: | 2016-07-02 | Release date: | 2017-05-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions. Structure, 25, 2017
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5GI4
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![BU of 5gi4 by Molmil](/molmil-images/mine/5gi4) | DEAD-box RNA helicase | Descriptor: | ATP-dependent RNA helicase DeaD | Authors: | Xu, L, Wang, L, Li, F, Wu, L, Shi, Y. | Deposit date: | 2016-06-22 | Release date: | 2017-05-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.244 Å) | Cite: | Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions. Structure, 25, 2017
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3FUL
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3FTZ
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![BU of 3ftz by Molmil](/molmil-images/mine/3ftz) | Leukotriene A4 hydrolase in complex with fragment 2-(pyridin-3-ylmethoxy)aniline | Descriptor: | 2-(pyridin-3-ylmethoxy)aniline, ACETATE ION, IMIDAZOLE, ... | Authors: | Davies, D.R. | Deposit date: | 2009-01-13 | Release date: | 2010-01-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis. J.Med.Chem., 53, 2010
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1MJT
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![BU of 1mjt by Molmil](/molmil-images/mine/1mjt) | CRYSTAL STRUCTURE OF SANOS, A BACTERIAL NITRIC OXIDE SYNTHASE OXYGENASE PROTEIN, IN COMPLEX WITH NAD+ AND SEITU | Descriptor: | ETHYLISOTHIOUREA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NITRIC-OXIDE SYNTHASE HOMOLOG, ... | Authors: | Bird, L.E, Ren, J, Stammers, D.K. | Deposit date: | 2002-08-28 | Release date: | 2003-01-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of SANOS, a Bacterial Nitric Oxide Synthase Oxygenase Protein from Staphylococcus aureus Structure, 10, 2002
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5YZ3
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![BU of 5yz3 by Molmil](/molmil-images/mine/5yz3) | Crystal structure of T2R-TTL-28 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Yu, Y, Chen, Q. | Deposit date: | 2017-12-12 | Release date: | 2018-10-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.545 Å) | Cite: | A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors. Cancer Res., 78, 2018
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2P0X
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![BU of 2p0x by Molmil](/molmil-images/mine/2p0x) | solution structure of a non-biological ATP-binding protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ZINC ION, abiotic ATP-binding, ... | Authors: | Mansy, S.S, Szostak, J.W, Chaput, J.C. | Deposit date: | 2007-03-01 | Release date: | 2007-08-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and Evolutionary Analysis of a Non-biological ATP-binding Protein J.Mol.Biol., 371, 2007
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3PL9
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![BU of 3pl9 by Molmil](/molmil-images/mine/3pl9) | Crystal structure of spinach minor light-harvesting complex CP29 at 2.80 angstrom resolution | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X.W, Li, M, Wan, T, Wang, L.F, Jia, C.J, Hou, Z.Q, Zhao, X.L, Zhang, J.P, Chang, W.R. | Deposit date: | 2010-11-14 | Release date: | 2011-02-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights into energy regulation of light-harvesting complex CP29 from spinach. Nat.Struct.Mol.Biol., 18, 2011
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3P08
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4GFG
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![BU of 4gfg by Molmil](/molmil-images/mine/4gfg) | Crystal structure of spleen tyrosine kinase complexed with r9021 | Descriptor: | 6-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(5,6-dimethylpyridin-2-yl)amino]pyridazine-3-carboxamide, Tyrosine-protein kinase SYK | Authors: | Lukacs, C, Slade, M. | Deposit date: | 2012-08-03 | Release date: | 2013-08-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A specific SYK inhibitor blocks B Cell Receptor, Fc Receptor, and Toll-like Receptor 9 pathways for the treatment of inflammatory diseases. To be Published
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5Y4B
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![BU of 5y4b by Molmil](/molmil-images/mine/5y4b) | Solution structure of yeast Fra2 | Descriptor: | BolA-like protein 2 | Authors: | Tang, Y.J, Chi, C.B, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2017-08-03 | Release date: | 2018-03-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3. J. Mol. Biol., 430, 2018
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7Z8Z
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![BU of 7z8z by Molmil](/molmil-images/mine/7z8z) | Crystal structure of the MEILB2-BRME1 2:2 core complex | Descriptor: | Break repair meiotic recombinase recruitment factor 1, Heat shock factor 2-binding protein | Authors: | Gurusaran, M, Davies, O.R. | Deposit date: | 2022-03-19 | Release date: | 2023-09-20 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic recombination. Nat Commun, 15, 2024
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7YMD
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![BU of 7ymd by Molmil](/molmil-images/mine/7ymd) | Cryo-EM structure of Nse1/3/4 | Descriptor: | Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosomes element 1 | Authors: | Qian, L, Jun, Z, Zhenguo, C, Wang, L. | Deposit date: | 2022-07-28 | Release date: | 2024-01-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.176 Å) | Cite: | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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8YDC
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![BU of 8ydc by Molmil](/molmil-images/mine/8ydc) | Crystal structure of a hammerhead ribozyme with pseudoknot | Descriptor: | DNA/RNA (5'-R(*AP*CP*AP*UP*GP*UP*CP*U)-D(P*C)-R(P*UP*GP*GP*GP*A)-3'), GUANOSINE-5'-TRIPHOSPHATE, ribozyme strand | Authors: | Liu, Y, Zhan, X. | Deposit date: | 2024-02-20 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | The structure and catalytic mechanism of a pseudoknot-containing hammerhead ribozyme. Nat Commun, 15, 2024
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4LWU
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![BU of 4lwu by Molmil](/molmil-images/mine/4lwu) | The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252 | Descriptor: | (2'S,3R,4'S,5'R)-N-(4-carbamoylphenyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | Authors: | Graves, B.J, Lukacs, C, Janson, C.A. | Deposit date: | 2013-07-28 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy. Bioorg.Med.Chem., 22, 2014
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8I3G
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![BU of 8i3g by Molmil](/molmil-images/mine/8i3g) | Crystal structure of Eaf3-Eaf7 complex | Descriptor: | Chromatin modification-related protein EAF3, Chromatin modification-related protein EAF7 | Authors: | Chen, Z, Xu, C. | Deposit date: | 2023-01-17 | Release date: | 2023-05-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4. Cell Discov, 9, 2023
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8I3F
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6KE3
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6KDF
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![BU of 6kdf by Molmil](/molmil-images/mine/6kdf) | Crystal structure of the alpha beta heterodimer of human IDH3 in APO form. | Descriptor: | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta | Authors: | Sun, P, Ding, J. | Deposit date: | 2019-07-02 | Release date: | 2019-09-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase. J.Biol.Chem., 294, 2019
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6KDE
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4NIE
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