1C5G
 
 | | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | Descriptor: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | Authors: | Goldsmith, E.J. | | Deposit date: | 1999-12-07 | | Release date: | 1999-12-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition.
Nat.Struct.Biol., 2, 1995
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5GIM
 | | Crystal structure of thrombin-avathrin complex | | Descriptor: | C-terminal peptide from Putative uncharacterized protein avahiru, N-terminal peptide from Putative uncharacterized protein avahiru, Thrombin light chain, ... | | Authors: | Kini, R.M, Koh, C.Y, Iyer, J.K, Swaminathan, K. | | Deposit date: | 2016-06-24 | | Release date: | 2017-05-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum.
FASEB J., 31, 2017
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7QO4
 | | 26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS) | | Descriptor: | 26S proteasome regulatory subunit RPN1, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | | Deposit date: | 2021-12-23 | | Release date: | 2022-06-01 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
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7N6P
 | | Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab | | Descriptor: | 1C3 Fab heavy chain, 1C3 Fab light chain | | Authors: | Milligan, J.C, Yu, X, Buck, T, Saphire, E.O. | | Deposit date: | 2021-06-08 | | Release date: | 2022-04-06 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
Cell, 185, 2022
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7SWD
 | | Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound | | Descriptor: | 1C11 scFv, 1C3 heavy chain, 1C3 light chain, ... | | Authors: | Milligan, J.C, Yu, X, Saphire, E.O. | | Deposit date: | 2021-11-19 | | Release date: | 2022-04-06 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
Cell, 185, 2022
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8VSG
 | | SARS-CoV-2 main protease with covalent inhibitor | | Descriptor: | (1R,2S,5S)-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-(1-phenylcyclopropane-1-carbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide, 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | Authors: | Bell, J.A, Bandera, A.M. | | Deposit date: | 2024-01-24 | | Release date: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.071 Å) | | Cite: | Exploiting high-energy hydration sites for the discovery of potent peptide aldehyde inhibitors of the SARS-CoV-2 main protease with cellular antiviral activity.
Bioorg.Med.Chem., 103, 2024
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3UV1
 | | Crystal structure a major allergen from dust mite | | Descriptor: | Der f 7 allergen | | Authors: | Tan, K.W, Kumar, T, Chew, F.T, Mok, Y.K. | | Deposit date: | 2011-11-29 | | Release date: | 2012-10-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Der f 7, a Dust Mite Allergen from Dermatophagoides farinae.
Plos One, 7, 2012
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6INU
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6INN
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6INV
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6VZI
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7C00
 | | Crystal structure of the SRCR domain of human SCARA5. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Scavenger receptor class A member 5 | | Authors: | Yu, B, He, Y. | | Deposit date: | 2020-04-29 | | Release date: | 2020-09-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Interactions of ferritin with scavenger receptor class A members.
J.Biol.Chem., 295, 2020
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7BZZ
 | | Crystal structure of the SRCR domain of mouse SCARA5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Scavenger receptor class A member 5 | | Authors: | Yu, B, He, Y. | | Deposit date: | 2020-04-29 | | Release date: | 2020-09-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Interactions of ferritin with scavenger receptor class A members.
J.Biol.Chem., 295, 2020
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6W03
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6HHF
 | | Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor Borussertib | | Descriptor: | Borussertib, RAC-alpha serine/threonine-protein kinase | | Authors: | Landel, I, Weisner, J, Mueller, M.P, Scheinpflug, R, Rauh, D. | | Deposit date: | 2018-08-28 | | Release date: | 2019-03-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib inKRAS-Mutant Pancreatic and Colorectal Cancer.
Cancer Res., 79, 2019
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3X13
 | | Crystal structure of HLA-B*0801.N80I | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ... | | Authors: | Vivian, J.P, Rossjohn, J. | | Deposit date: | 2014-10-24 | | Release date: | 2014-12-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
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6IOE
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6INO
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3X11
 | | Crystal structure of HLA-B*57:01.I80N.L82R.R83G | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | | Authors: | Vivian, J.P, Rossjohn, J. | | Deposit date: | 2014-10-24 | | Release date: | 2014-12-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
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3X12
 | | Crystal structure of HLA-B*57:01.I80N | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | | Authors: | Vivian, J.P, Rossjohn, J. | | Deposit date: | 2014-10-24 | | Release date: | 2014-12-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
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3WYR
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3X14
 | | Crystal structure of HLA-B*0801.N80I.R82L.G83R | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ... | | Authors: | Vivian, J.P, Rossjohn, J. | | Deposit date: | 2014-10-25 | | Release date: | 2014-12-24 | | Last modified: | 2015-04-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
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8K8H
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1DAN
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5B38
 | | KIR3DL1*005 in complex with HLA-B*57:01 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Vivian, J.P, Rossjohn, J. | | Deposit date: | 2016-02-12 | | Release date: | 2016-03-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition
J.Exp.Med., 213, 2016
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