3X12

Crystal structure of HLA-B*57:01.I80N

Summary for 3X12

• Entry DOI: 10.2210/pdb3x12/pdb
• Related: 2RFX 3x11 3x13 3x14
• Descriptor: HLA class I histocompatibility antigen, B-57 alpha chain, Beta-2-microglobulin, Ig kappa chain C region, ... (4 entities in total)
• Functional Keywords: immunoglobulin fold, immunity, antigen presentation, immune receptors, lilr, tcr, kir, plasma membrane, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P18465; Secreted : P61769
• Total number of polymer chains: 3
• Total formula weight: 44451.39

Authors

Vivian, J.P.,Rossjohn, J. (deposition date: 2014-10-24, release date: 2014-12-24, Last modification date: 2023-11-08)

• Primary citation: Saunders, P.M.,Vivian, J.P.,Baschuk, N.,Beddoe, T.,Widjaja, J.,O'Connor, G.M.,Hitchen, C.,Pymm, P.,Andrews, D.M.,Gras, S.,McVicar, D.W.,Rossjohn, J.,Brooks, A.G.; The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope; J.Immunol., 194:781-789, 2015; PubMed: 25480565; DOI: 10.4049/jimmunol.1402542

Experimental method

X-RAY DIFFRACTION (1.8 Å)