5GIM
Crystal structure of thrombin-avathrin complex
Summary for 5GIM
| Entry DOI | 10.2210/pdb5gim/pdb |
| Descriptor | Thrombin light chain, thrombin heavy chain, N-terminal peptide from Putative uncharacterized protein avahiru, ... (5 entities in total) |
| Functional Keywords | hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Secreted, extracellular space: P00734 |
| Total number of polymer chains | 4 |
| Total formula weight | 37037.17 |
| Authors | Kini, R.M.,Koh, C.Y.,Iyer, J.K.,Swaminathan, K. (deposition date: 2016-06-24, release date: 2017-05-03, Last modification date: 2023-11-08) |
| Primary citation | Iyer, J.K.,Koh, C.Y.,Kazimirova, M.,Roller, L.,Jobichen, C.,Swaminathan, K.,Mizuguchi, J.,Iwanaga, S.,Nuttall, P.A.,Chan, M.Y.,Kini, R.M. Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum. FASEB J., 31:2981-2995, 2017 Cited by PubMed: 28363953DOI: 10.1096/fj.201601216R PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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