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5ZQZ
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BU of 5zqz by Molmil
Structure of human mitochondrial trifunctional protein, tetramer
Descriptor: Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
Authors:Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J.
Deposit date:2018-04-20
Release date:2018-06-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZRV
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BU of 5zrv by Molmil
Structure of human mitochondrial trifunctional protein, octamer
Descriptor: Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta
Authors:Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J.
Deposit date:2018-04-25
Release date:2018-06-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5XOO
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BU of 5xoo by Molmil
The structure of hydra Fam20 with sugar
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE, Glycosaminoglycan xylosylkinase, ...
Authors:Zhang, H, Xiao, J.
Deposit date:2017-05-29
Release date:2018-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
4GY5
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BU of 4gy5 by Molmil
Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3
Descriptor: E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION
Authors:Cheng, J, Yang, Y, Fang, J, Xiao, J, Zhu, T, Chen, F, Wang, P, Xu, Y.
Deposit date:2012-09-05
Release date:2012-11-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.956 Å)
Cite:Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
5YH3
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BU of 5yh3 by Molmil
The structure of hFam20C and hFam20A complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Extracellular serine/threonine protein kinase FAM20C, Pseudokinase FAM20A
Authors:Zhu, Q, Xiao, J.
Deposit date:2017-09-27
Release date:2018-04-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
5YH0
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BU of 5yh0 by Molmil
The structure of DrFam20C1
Descriptor: DrFam20C1
Authors:Zhang, H, Xiao, J.
Deposit date:2017-09-27
Release date:2018-04-11
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
5YH2
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BU of 5yh2 by Molmil
The structure of DrFam20C1 and hFam20A complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Family with sequence similarity 20, member Ca, ...
Authors:Zhang, H, Xiao, J.
Deposit date:2017-09-27
Release date:2018-04-11
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
5Z5K
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BU of 5z5k by Molmil
Structure of the DCC-Draxin complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Draxin, ...
Authors:Liu, Y, Xiao, J, Wang, J.
Deposit date:2018-01-18
Release date:2018-06-20
Last modified:2021-03-10
Method:X-RAY DIFFRACTION (2.493 Å)
Cite:Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.
Neuron, 97, 2018
1PGY
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BU of 1pgy by Molmil
Solution structure of the UBA domain in Saccharomyces cerevisiae protein, Swa2p
Descriptor: Swa2p
Authors:Chim, N, Gall, W.E, Xiao, J, Harris, M.P, Graham, T.R, Krezel, A.M.
Deposit date:2003-05-28
Release date:2004-03-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the ubiquitin-binding domain in Swa2p from Saccharomyces cerevisiae.
PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
6G9B
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BU of 6g9b by Molmil
Crystal structure of Ebolavirus glycoprotein in complex with imipramine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, ...
Authors:Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I.
Deposit date:2018-04-10
Release date:2018-05-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
J. Med. Chem., 61, 2018
6G95
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BU of 6g95 by Molmil
Crystal structure of Ebolavirus glycoprotein in complex with thioridazine
Descriptor: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
Authors:Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I.
Deposit date:2018-04-10
Release date:2018-05-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
J. Med. Chem., 61, 2018
6G9I
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BU of 6g9i by Molmil
Crystal structure of Ebolavirus glycoprotein in complex with clomipramine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, Envelope glycoprotein,Envelope glycoprotein, ...
Authors:Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I.
Deposit date:2018-04-10
Release date:2018-05-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
J. Med. Chem., 61, 2018
6K0J
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BU of 6k0j by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor
Descriptor: 3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 2
Authors:Tiantian, W, Xiao, J.
Deposit date:2019-05-06
Release date:2019-11-20
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.352 Å)
Cite:Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.
Proc.Natl.Acad.Sci.USA, 116, 2019
6KXS
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BU of 6kxs by Molmil
Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Li, Y, Wang, G, Xiao, J.
Deposit date:2019-09-12
Release date:2020-02-05
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into immunoglobulin M.
Science, 367, 2020
6LXW
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BU of 6lxw by Molmil
Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA
Descriptor: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ...
Authors:Wang, Y, Wang, G, Li, Y, Xiao, J.
Deposit date:2020-02-12
Release date:2020-05-27
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
6LX3
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BU of 6lx3 by Molmil
Cryo-EM structure of human secretory immunoglobulin A
Descriptor: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor
Authors:Wang, Y, Wang, G, Li, Y, Xiao, J.
Deposit date:2020-02-10
Release date:2020-05-27
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
2CKA
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BU of 2cka by Molmil
Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction
Descriptor: CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8
Authors:Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E.
Deposit date:2006-04-14
Release date:2007-05-08
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published
2CKC
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BU of 2ckc by Molmil
Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction
Descriptor: CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
Authors:Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E.
Deposit date:2006-04-14
Release date:2007-05-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published
7V20
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BU of 7v20 by Molmil
CryoEM structure of del68-76/del679-688 prefusion-stabilized spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Du, S, Xiao, J.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:CryoEM structure of del68-76/del679-688 prefusion-stabilized spike
To Be Published
7V22
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BU of 7v22 by Molmil
Local CryoEM structure del68-76/del679-688 prefusion-stabilized spike
Descriptor: Spike glycoprotein
Authors:Du, S, Xiao, J.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Local CryoEM structure del68-76/del679-688 prefusion-stabilized spike
To Be Published
7V23
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BU of 7v23 by Molmil
CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Du, S, Xiao, J.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9
To Be Published
7V24
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BU of 7v24 by Molmil
Local CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9
Descriptor: Spike glycoprotein, the heavy chain of N12-9 Fab, the lignt chain of N12-9 Fab
Authors:Du, S, Xiao, J.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Local CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9
To Be Published
7E7Y
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BU of 7e7y by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-623 Fab
Descriptor: BD-623 Fab H, BD-623 Fab L, Spike protein S1
Authors:Wei, Y, Xiao, J.
Deposit date:2021-02-28
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E7X
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BU of 7e7x by Molmil
SARS-CoV-2 Spike Protein N terminal domain in Complex with N11 Fab
Descriptor: N11 Fab Light chain, N11 Fab heavy chain, Spike protein S1
Authors:Zhang, Z, Shuo, D, Xiao, J.
Deposit date:2021-02-28
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E8C
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BU of 7e8c by Molmil
SARS-CoV-2 S-6P in complex with 9 Fabs
Descriptor: 368-2 H, 368-2 L, 604 H, ...
Authors:Du, S, Xiao, J, Zhang, Z.
Deposit date:2021-03-01
Release date:2021-06-09
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021

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