6G9B

Crystal structure of Ebolavirus glycoprotein in complex with imipramine

Summary for 6G9B

• Entry DOI: 10.2210/pdb6g9b/pdb
• Related: 6G95
• Descriptor: Envelope glycoprotein,Envelope glycoprotein, Envelope glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: ebolavirus glycoprotein, imipramine, protein drug complex, viral protein
• Biological source: Zaire ebolavirus (strain Mayinga-76) (ZEBOV); More
• Total number of polymer chains: 2
• Total formula weight: 57882.05

Authors

Zhao, Y.,Ren, J.,Fry, E.E.,Xiao, J.,Townsend, A.R.,Stuart, D.I. (deposition date: 2018-04-10, release date: 2018-05-23, Last modification date: 2020-07-29)

• Primary citation: Zhao, Y.,Ren, J.,Fry, E.E.,Xiao, J.,Townsend, A.R.,Stuart, D.I.; Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.; J. Med. Chem., 61:4938-4945, 2018; PubMed: 29741894; DOI: 10.1021/acs.jmedchem.8b00350

Experimental method

X-RAY DIFFRACTION (2.26 Å)