6G9B
Crystal structure of Ebolavirus glycoprotein in complex with imipramine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Envelope glycoprotein,Envelope glycoprotein | polymer | 330 | 36302.7 | 1 | UniProt (Q05320) Pfam (PF01611) In PDB | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) | GP1,2,GP,GP1,2,GP |
2 | B | Envelope glycoprotein | polymer | 168 | 18922.3 | 1 | UniProt (Q05320) Pfam (PF22307) In PDB | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) | GP1,2,GP |
3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
5 | A, B | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
6 | A, B | 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE | non-polymer | 280.4 | 2 | Chemie (IXX) | |||
7 | A, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
8 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 32 - 310 (UniProt: Q05320)
A: 478 - 515 (UniProt: Q05320)
B: 502 - 632 (UniProt: Q05320)
PDB | External Database | Details |
---|---|---|
Glu 28 | - | expression tag |
Thr 29 | - | expression tag |
Gly 30 | - | expression tag |
Arg 31 | - | expression tag |
Ala 42 | Thr 42 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 311 | - | linker |
Unk 471 | - | linker |
Unk 472 | - | linker |
Unk 473 | - | linker |
Unk 474 | - | linker |
Unk 475 | - | linker |
Unk 476 | - | linker |
Unk 477 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 613 | His 613 | engineered mutation |
Gly 633 | - | expression tag |
Ser 634 | - | expression tag |
Gly 635 | - | expression tag |
Tyr 636 | - | expression tag |
Ile 637 | - | expression tag |
Pro 638 | - | expression tag |
Glu 639 | - | expression tag |
Ala 640 | - | expression tag |
Pro 641 | - | expression tag |
Arg 642 | - | expression tag |
Asp 643 | - | expression tag |
Gly 644 | - | expression tag |
Gln 645 | - | expression tag |
Ala 646 | - | expression tag |
Tyr 647 | - | expression tag |
Val 648 | - | expression tag |
Arg 649 | - | expression tag |
Lys 650 | - | expression tag |
Asp 651 | - | expression tag |
Gly 652 | - | expression tag |
Glu 653 | - | expression tag |
Trp 654 | - | expression tag |
Val 655 | - | expression tag |
Leu 656 | - | expression tag |
Leu 657 | - | expression tag |
Ser 658 | - | expression tag |
Thr 659 | - | expression tag |
Phe 660 | - | expression tag |
Leu 661 | - | expression tag |
Gly 662 | - | expression tag |
Thr 663 | - | expression tag |
His 664 | - | expression tag |
His 665 | - | expression tag |
His 666 | - | expression tag |
His 667 | - | expression tag |
His 668 | - | expression tag |
His 669 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 55225.0 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 2232.6 | |
All* | Total formula weight | 57882.0 |