6G9I
Crystal structure of Ebolavirus glycoprotein in complex with clomipramine
Summary for 6G9I
Entry DOI | 10.2210/pdb6g9i/pdb |
Descriptor | Envelope glycoprotein,Envelope glycoprotein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | ebolavirus glycoprotein, clomipramine, protein drug complex, viral protein |
Biological source | Ebola virus - Mayinga, Zaire, 1976 More |
Total number of polymer chains | 2 |
Total formula weight | 57541.78 |
Authors | Zhao, Y.,Ren, J.,Fry, E.E.,Xiao, J.,Townsend, A.R.,Stuart, D.I. (deposition date: 2018-04-10, release date: 2018-05-23, Last modification date: 2020-07-29) |
Primary citation | Zhao, Y.,Ren, J.,Fry, E.E.,Xiao, J.,Townsend, A.R.,Stuart, D.I. Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs. J. Med. Chem., 61:4938-4945, 2018 Cited by PubMed: 29741894DOI: 10.1021/acs.jmedchem.8b00350 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
Download full validation report