6G9I

Crystal structure of Ebolavirus glycoprotein in complex with clomipramine

Summary for 6G9I

Entry DOI	10.2210/pdb6g9i/pdb
Descriptor	Envelope glycoprotein,Envelope glycoprotein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	ebolavirus glycoprotein, clomipramine, protein drug complex, viral protein
Biological source	Ebola virus - Mayinga, Zaire, 1976 More
Total number of polymer chains	2
Total formula weight	57541.78
Authors	Zhao, Y.,Ren, J.,Fry, E.E.,Xiao, J.,Townsend, A.R.,Stuart, D.I. (deposition date: 2018-04-10, release date: 2018-05-23, Last modification date: 2020-07-29)
Primary citation	Zhao, Y.,Ren, J.,Fry, E.E.,Xiao, J.,Townsend, A.R.,Stuart, D.I. Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs. J. Med. Chem., 61:4938-4945, 2018 Cited by PubMed: 29741894 DOI: 10.1021/acs.jmedchem.8b00350 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation