6HNU
| Crystal structure of the aminotransferase Aro8 from C. Albicans with ligands | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aromatic amino acid aminotransferase I, ... | Authors: | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | Deposit date: | 2018-09-17 | Release date: | 2019-02-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties. J.Struct.Biol., 205, 2019
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6HND
| Crystal structure of the aromatic aminotransferase Aro9 from C. Albicans | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Aromatic-amino-acid:2-oxoglutarate transaminase, POTASSIUM ION, ... | Authors: | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | Deposit date: | 2018-09-14 | Release date: | 2019-02-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties. J.Struct.Biol., 205, 2019
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6HNV
| Crystal structure of aminotransferase Aro9 from C. Albicans with ligands | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINOHEXANEDIOIC ACID, 2-OXOADIPIC ACID, ... | Authors: | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | Deposit date: | 2018-09-17 | Release date: | 2019-02-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties. J.Struct.Biol., 205, 2019
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6HNB
| Crystal structure of aminotransferase Aro8 from Candida albicans | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aromatic amino acid aminotransferase I, CHLORIDE ION, ... | Authors: | Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I. | Deposit date: | 2018-09-14 | Release date: | 2019-02-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties. J.Struct.Biol., 205, 2019
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1LNL
| Structure of deoxygenated hemocyanin from Rapana thomasiana | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, hemocyanin | Authors: | Perbandt, M, Guthoehrlein, E.W, Rypniewski, W, Idakieva, K, Stoeva, S, Voelter, W, Genov, N, Betzel, C. | Deposit date: | 2002-05-03 | Release date: | 2003-06-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The structure of a functional unit from the wall of a gastropod hemocyanin offers a possible mechanism for cooperativity Biochemistry, 42, 2003
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5EME
| Complex of RNA r(GCAGCAGC) with antisense PNA p(CTGCTGC) | Descriptor: | Antisense PNA strand, CHLORIDE ION, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | Authors: | Kiliszek, A, Banaszak, K, Dauter, Z, Rypniewski, W. | Deposit date: | 2015-11-06 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs. Nucleic Acids Res., 44, 2016
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5EMG
| Crystal structures of PNA p(GCTGCTGC)2 duplex containing T-T mismatches | Descriptor: | CHLORIDE ION, GPN-CPN-TPN-GPN-CPN-TPN-GPN-CPN, SODIUM ION | Authors: | Kiliszek, A, Banaszak, K, Dauter, Z, Rypniewski, W. | Deposit date: | 2015-11-06 | Release date: | 2016-01-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs. Nucleic Acids Res., 44, 2016
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5EMF
| Crystal structure of RNA r(GCUGCUGC) with antisense PNA p(GCAGCAGC) | Descriptor: | CHLORIDE ION, RNA (5'-R(*GP*CP*UP*GP*CP*UP*GP*C)-3'), antisense PNA p(GCAGCAGC) | Authors: | Kiliszek, A, Banaszak, K, Dauter, Z, Rypniewski, W. | Deposit date: | 2015-11-06 | Release date: | 2016-01-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs. Nucleic Acids Res., 44, 2016
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6QIS
| Crystal structure of CAG repeats with synthetic CMBL3a compound (model II) | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3'), SULFATE ION | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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6QIR
| Crystal structure of CAG repeats with synthetic CMBL3a compound (model I) | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.531 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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6QIV
| Crystal structure of seleno-derivative CAG repeats with synthetic CMBL4 compound | Descriptor: | CMBL4, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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6QIQ
| Crystal structure of seleno-derivative CAG repeats with synthetic CMBL3a compound | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*G)-D(P*(CSL))-R(P*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Micura, R, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.519 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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6QIT
| Crystal structure of CAG repeats with synthetic CMBL3b compound | Descriptor: | CMBL3a, RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3') | Authors: | Kiliszek, A, Blaszczyk, L, Rypniewski, W, Nakatani, K. | Deposit date: | 2019-01-21 | Release date: | 2019-09-25 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats. Nucleic Acids Res., 47, 2019
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4EZ8
| Crystal structure of mouse thymidylate sythase in ternary complex with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate and the cofactor product, dihydrofolate | Descriptor: | 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate), DIHYDROFOLIC ACID, GLYCEROL, ... | Authors: | Dowiercial, A, Jarmula, A, Rypniewski, W, Wilk, P, Kierdaszuk, B, Banaszak, K, Gorecka, K, Rode, W. | Deposit date: | 2012-05-02 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Crystal structures of complexes of mouse thymidylate synthase
crystallized with N4-OH-dCMP alone or in the presence of
N5,10-methylenetetrahydrofolate Pteridines, 2013
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4IRR
| Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thymidylate synthase | Authors: | Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. | Deposit date: | 2013-01-15 | Release date: | 2014-01-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP To be Published
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4ISW
| Crystal Structure of Phosphorylated C.elegans Thymidylate Synthase in Complex with dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase | Authors: | Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. | Deposit date: | 2013-01-17 | Release date: | 2013-12-11 | Last modified: | 2014-01-15 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Crystal structure of phosphoramide-phosphorylated thymidylate synthase reveals pSer127, reflecting probably pHis to pSer phosphotransfer. Bioorg.Chem., 52C, 2013
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4IQB
| High Resolution Crystal Structure of C.elegans Thymidylate Synthase | Descriptor: | SULFATE ION, Thymidylate synthase | Authors: | Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. | Deposit date: | 2013-01-11 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J. Mol. Graph. Model., 77, 2017
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8AMG
| Crystal structure of AUGUGGCAU duplex with barium ions (model 1) | Descriptor: | BARIUM ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3') | Authors: | Kiliszek, A, Rypniewski, W. | Deposit date: | 2022-08-03 | Release date: | 2022-11-23 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
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8AMM
| Crystal structure of AUGUGGCAU duplex with cesium ions | Descriptor: | CESIUM ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3') | Authors: | Kiliszek, A, Rypniewski, W. | Deposit date: | 2022-08-03 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
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8AMJ
| Crystal structure of unliganded AUGUGGCAU duplex | Descriptor: | ACETATE ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3'), SULFATE ION | Authors: | Kiliszek, A, Rypniewski, W. | Deposit date: | 2022-08-03 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
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8AMI
| Crystal structure of AUGUGGCAU duplex with barium ions (model 2) | Descriptor: | BARIUM ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3'), SODIUM ION | Authors: | Kiliszek, A, Rypniewski, W. | Deposit date: | 2022-08-03 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
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8AML
| Crystal structure of AUGUGGCAU duplex with cadmium ions | Descriptor: | CADMIUM ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3') | Authors: | Kiliszek, A, Rypniewski, W. | Deposit date: | 2022-08-03 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
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8AMK
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8AMN
| Crystal structure of AUGUGGCAU duplex with strontium ions | Descriptor: | RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3'), STRONTIUM ION | Authors: | Kiliszek, A, Rypniewski, W. | Deposit date: | 2022-08-03 | Release date: | 2022-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
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3GM7
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