5EME

Complex of RNA r(GCAGCAGC) with antisense PNA p(CTGCTGC)

Summary for 5EME

• Entry DOI: 10.2210/pdb5eme/pdb
• Descriptor: RNA (5'-R(*GP*CP*AP*GP*CP*AP*GP*C)-3'), Antisense PNA strand, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: cag repeats, rna/pna, pna antisense oligomer, poly-q dieseases, rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 4821.63

Authors

Kiliszek, A.,Banaszak, K.,Dauter, Z.,Rypniewski, W. (deposition date: 2015-11-06, release date: 2016-01-13, Last modification date: 2024-01-10)

• Primary citation: Kiliszek, A.,Banaszak, K.,Dauter, Z.,Rypniewski, W.; The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs.; Nucleic Acids Res., 44:1937-1943, 2016; PubMed: 26717983; DOI: 10.1093/nar/gkv1513

Experimental method

X-RAY DIFFRACTION (1.15 Å)