5EMF

Crystal structure of RNA r(GCUGCUGC) with antisense PNA p(GCAGCAGC)

Summary for 5EMF

• Entry DOI: 10.2210/pdb5emf/pdb
• Related: 5EME
• Descriptor: RNA (5'-R(*GP*CP*UP*GP*CP*UP*GP*C)-3'), antisense PNA p(GCAGCAGC), CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: cug repeats, rna/pna duplex, antisense pna, myotonic dystrophy type 1, rna
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 4793.58

Authors

Kiliszek, A.,Banaszak, K.,Dauter, Z.,Rypniewski, W. (deposition date: 2015-11-06, release date: 2016-01-13, Last modification date: 2023-11-15)

• Primary citation: Kiliszek, A.,Banaszak, K.,Dauter, Z.,Rypniewski, W.; The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs.; Nucleic Acids Res., 44:1937-1943, 2016; PubMed: 26717983; DOI: 10.1093/nar/gkv1513

Experimental method

X-RAY DIFFRACTION (1.14 Å)