2Z43
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![BU of 2z43 by Molmil](/molmil-images/mine/2z43) | Structure of a twinned crystal of RadA | Descriptor: | DNA repair and recombination protein radA | Authors: | Chen, L.T, Ko, T.P, Wang, A.H.J, Wang, T.F. | Deposit date: | 2007-06-12 | Release date: | 2007-11-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RADA protein Plos One, 2, 2007
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2ZUB
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![BU of 2zub by Molmil](/molmil-images/mine/2zub) | Left handed RadA | Descriptor: | DNA repair and recombination protein radA | Authors: | Chang, Y.W, Ko, T.P, Wang, T.F, Wang, A.H.J. | Deposit date: | 2008-10-15 | Release date: | 2009-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity Plos One, 4, 2009
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2ZUC
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![BU of 2zuc by Molmil](/molmil-images/mine/2zuc) | |
2ZUD
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7C8T
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![BU of 7c8t by Molmil](/molmil-images/mine/7c8t) | Complex Structure of SARS-CoV-2 3CL Protease with TG-0205221 | Descriptor: | 3C-like proteinase, N-[(BENZYLOXY)CARBONYL]-O-(TERT-BUTYL)-L-THREONYL-3-CYCLOHEXYL-N-[(1S)-2-HYDROXY-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}ETHYL]-L-ALANINAMIDE | Authors: | Lee, C.C, Wang, A.H.J, Kuo, C.J, Liang, P.H. | Deposit date: | 2020-06-03 | Release date: | 2020-06-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Complex Structures and Cellular Activities of the Potent SARS-CoV-2 3CLpro Inhibitors Guiding Drug Discovery Against COVID-19 To Be Published
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7C8R
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![BU of 7c8r by Molmil](/molmil-images/mine/7c8r) | Complex Structure of SARS-CoV-2 3CL Protease with TG-0203770 | Descriptor: | 3C-like proteinase, ethyl (4R)-4-[[(2S)-4-methyl-2-[[(2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoyl]amino]pentanoyl]amino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate | Authors: | Lee, C.C, Wang, A.H.J, Kuo, C.J, Liang, P.H. | Deposit date: | 2020-06-03 | Release date: | 2020-06-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Complex Structures and Cellular Activities of the Potent SARS-CoV-2 3CLpro Inhibitors Guiding Drug Discovery Against COVID-19 To Be Published
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7CGA
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3ADZ
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![BU of 3adz by Molmil](/molmil-images/mine/3adz) | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with intermediate PSPP | Descriptor: | Dehydrosqualene synthase, MAGNESIUM ION, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E. | Deposit date: | 2010-01-31 | Release date: | 2010-11-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Mechanism of action and inhibition of dehydrosqualene synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
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3AE0
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![BU of 3ae0 by Molmil](/molmil-images/mine/3ae0) | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with geranylgeranyl thiopyrophosphate | Descriptor: | Dehydrosqualene synthase, MAGNESIUM ION, phosphonooxy-[(10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]sulfanyl-phosphinic acid | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E. | Deposit date: | 2010-01-31 | Release date: | 2010-11-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Mechanism of action and inhibition of dehydrosqualene synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
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2ZY1
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![BU of 2zy1 by Molmil](/molmil-images/mine/2zy1) | Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-830 | Descriptor: | Dehydrosqualene synthase, dipotassium (2-oxo-2-{[3-(3-phenoxyphenyl)propyl]amino}ethyl)phosphonate | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H.J, Oldfield, E. | Deposit date: | 2009-01-10 | Release date: | 2009-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. J.Med.Chem., 52, 2009
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3P19
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![BU of 3p19 by Molmil](/molmil-images/mine/3p19) | Improved NADPH-dependent Blue Fluorescent Protein | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative blue fluorescent protein | Authors: | Kao, T.H, Chen, Y, Pai, C.H, Wang, A.H.J. | Deposit date: | 2010-09-30 | Release date: | 2011-07-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of a NADPH-dependent blue fluorescent protein revealed the unique role of Gly176 on the fluorescence enhancement. J.Struct.Biol., 174, 2011
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3PB4
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![BU of 3pb4 by Molmil](/molmil-images/mine/3pb4) | Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase at pH 6.0 | Descriptor: | Glutaminyl-peptide cyclotransferase-like protein, ZINC ION | Authors: | Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J. | Deposit date: | 2010-10-20 | Release date: | 2011-02-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding J.Biol.Chem., 286, 2011
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3PBB
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![BU of 3pbb by Molmil](/molmil-images/mine/3pbb) | Crystal structure of human secretory glutaminyl cyclase in complex with PBD150 | Descriptor: | 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, Glutaminyl-peptide cyclotransferase, ZINC ION | Authors: | Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J. | Deposit date: | 2010-10-20 | Release date: | 2011-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding J.Biol.Chem., 286, 2011
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3PB6
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![BU of 3pb6 by Molmil](/molmil-images/mine/3pb6) | Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase at pH 6.5 | Descriptor: | CACODYLATE ION, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION | Authors: | Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J. | Deposit date: | 2010-10-20 | Release date: | 2011-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding J.Biol.Chem., 286, 2011
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3PB7
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![BU of 3pb7 by Molmil](/molmil-images/mine/3pb7) | Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex with PBD150 | Descriptor: | 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION | Authors: | Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J. | Deposit date: | 2010-10-20 | Release date: | 2011-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding J.Biol.Chem., 286, 2011
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3PB9
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![BU of 3pb9 by Molmil](/molmil-images/mine/3pb9) | Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex with 1-benzylimidazole | Descriptor: | 1-BENZYL-1H-IMIDAZOLE, Glutaminyl-peptide cyclotransferase-like protein, ZINC ION | Authors: | Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J. | Deposit date: | 2010-10-20 | Release date: | 2011-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding J.Biol.Chem., 286, 2011
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3PBE
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![BU of 3pbe by Molmil](/molmil-images/mine/3pbe) | Crystal structure of the mutant W207F of human secretory glutaminyl cyclase | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | Authors: | Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J. | Deposit date: | 2010-10-20 | Release date: | 2011-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding J.Biol.Chem., 286, 2011
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3PB8
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![BU of 3pb8 by Molmil](/molmil-images/mine/3pb8) | Crystal structure of the catalytic domain of human Golgi-resident glutaminyl cyclase in complex with N-acetylhistamine | Descriptor: | Glutaminyl-peptide cyclotransferase-like protein, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE, ZINC ION | Authors: | Huang, K.F, Liaw, S.S, Huang, W.L, Chia, C.Y, Lo, Y.C, Chen, Y.L, Wang, A.H.J. | Deposit date: | 2010-10-20 | Release date: | 2011-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding J.Biol.Chem., 286, 2011
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2DXP
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2E9A
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![BU of 2e9a by Molmil](/molmil-images/mine/2e9a) | E. coli undecaprenyl pyrophosphate synthase in complex with BPH-628 | Descriptor: | (1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase | Authors: | Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J. | Deposit date: | 2007-01-24 | Release date: | 2007-06-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E9C
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![BU of 2e9c by Molmil](/molmil-images/mine/2e9c) | E. coli undecaprenyl pyrophosphate synthase in complex with BPH-675 | Descriptor: | 1-HYDROXY-2-[3'-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase | Authors: | Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J. | Deposit date: | 2007-01-24 | Release date: | 2007-06-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E9D
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![BU of 2e9d by Molmil](/molmil-images/mine/2e9d) | E. coli undecaprenyl pyrophosphate synthase in complex with BPH-676 | Descriptor: | Undecaprenyl pyrophosphate synthetase, [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID) | Authors: | Guo, R.T, Cao, R, Ko, T.P, Liang, P.H, Oldfield, E, Wang, A.H.J. | Deposit date: | 2007-01-24 | Release date: | 2007-06-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E98
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![BU of 2e98 by Molmil](/molmil-images/mine/2e98) | E. coli undecaprenyl pyrophosphate synthase in complex with BPH-629 | Descriptor: | Undecaprenyl pyrophosphate synthetase, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID | Authors: | Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J. | Deposit date: | 2007-01-24 | Release date: | 2007-06-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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2FA5
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![BU of 2fa5 by Molmil](/molmil-images/mine/2fa5) | The crystal structure of an unliganded multiple antibiotic-resistance repressor (MarR) from Xanthomonas campestris | Descriptor: | CHLORIDE ION, transcriptional regulator marR/emrR family | Authors: | Chin, K.H, Tu, Z.L, Li, J.N, Chou, C.C, Wang, A.H.J, Chou, S.H. | Deposit date: | 2005-12-06 | Release date: | 2006-11-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of XC1739: a putative multiple antibiotic-resistance repressor (MarR) from Xanthomonas campestris at 1.8 A resolution Proteins, 65, 2006
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2GBZ
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![BU of 2gbz by Molmil](/molmil-images/mine/2gbz) | The Crystal Structure of XC847 from Xanthomonas campestris: a 3-5 Oligoribonuclease of DnaQ fold family with a Novel Opposingly-Shifted Helix | Descriptor: | MAGNESIUM ION, Oligoribonuclease | Authors: | Chin, K.H, Yang, C.Y, Chou, C.C, Wang, A.H.J, Chou, S.H. | Deposit date: | 2006-03-12 | Release date: | 2007-01-16 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of XC847 from Xanthomonas campestris: a 3'-5' oligoribonuclease of DnaQ fold family with a novel opposingly shifted helix Proteins, 65, 2006
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