2E9C
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-675
Summary for 2E9C
Entry DOI | 10.2210/pdb2e9c/pdb |
Related | 1X06 1X07 1X08 1X09 2E98 2E99 2E9A 2E9D |
Descriptor | Undecaprenyl pyrophosphate synthetase, 1-HYDROXY-2-[3'-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC ACID (3 entities in total) |
Functional Keywords | cell wall, prenyltransferase, farnesyl pyrophosphate, bisphosphonate, antibiotic, transferase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 59216.07 |
Authors | Guo, R.T.,Ko, T.P.,Cao, R.,Liang, P.H.,Oldfield, E.,Wang, A.H.J. (deposition date: 2007-01-24, release date: 2007-06-12, Last modification date: 2023-10-25) |
Primary citation | Guo, R.T.,Cao, R.,Liang, P.H.,Ko, T.P.,Chang, T.H.,Hudock, M.P.,Jeng, W.Y.,Chen, C.K.M.,Zhang, Y.,Song, Y.,Kuo, C.J.,Yin, F.,Oldfield, E.,Wang, A.H.J. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104:10022-10027, 2007 Cited by PubMed: 17535895DOI: 10.1073/pnas.0702254104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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