8PI5
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8PI4
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8PI6
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![BU of 8pi6 by Molmil](/molmil-images/mine/8pi6) | Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension | Descriptor: | Insulin B chain,Insulin A chain | Authors: | Johansson, E, Schluckebier, G. | Deposit date: | 2023-06-21 | Release date: | 2023-11-08 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
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4AJX
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![BU of 4ajx by Molmil](/molmil-images/mine/4ajx) | Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | Descriptor: | IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ... | Authors: | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | Deposit date: | 2012-02-20 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
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4AKJ
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![BU of 4akj by Molmil](/molmil-images/mine/4akj) | Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | Deposit date: | 2012-02-23 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
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4AJZ
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![BU of 4ajz by Molmil](/molmil-images/mine/4ajz) | Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | Deposit date: | 2012-02-21 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
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4AK0
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![BU of 4ak0 by Molmil](/molmil-images/mine/4ak0) | Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I. | Deposit date: | 2012-02-21 | Release date: | 2013-01-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec. Biochemistry, 52, 2013
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2VJZ
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![BU of 2vjz by Molmil](/molmil-images/mine/2vjz) | Crystal structure form ultalente insulin microcrystals | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. | Deposit date: | 2007-12-14 | Release date: | 2008-09-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Ultralente-A Microcrystalline Insulin Suspension. Proteins, 74, 2009
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2W44
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![BU of 2w44 by Molmil](/molmil-images/mine/2w44) | Structure DeltaA1-A4 insulin | Descriptor: | CHLORIDE ION, INSULIN, RESORCINOL, ... | Authors: | Thorsoee, K.S, Schlein, M, Brandt, J, Schluckebier, G, Naver, H. | Deposit date: | 2008-11-21 | Release date: | 2009-12-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform. Biochemistry, 49, 2010
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2WFU
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![BU of 2wfu by Molmil](/molmil-images/mine/2wfu) | Crystal structure of DILP5 variant DB | Descriptor: | PROBABLE INSULIN-LIKE PEPTIDE 5 A CHAIN, PROBABLE INSULIN-LIKE PEPTIDE 5 B CHAIN | Authors: | Kulahin, N, Schluckebier, G, Sajid, W, De Meyts, P. | Deposit date: | 2009-04-15 | Release date: | 2010-05-26 | Last modified: | 2012-04-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Biological Properties of the Drosophila Insulin-Like Peptide 5 Show Evolutionary Conservation. J.Biol.Chem., 286, 2011
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2WFV
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![BU of 2wfv by Molmil](/molmil-images/mine/2wfv) | Crystal structure of DILP5 variant C4 | Descriptor: | PROBABLE INSULIN-LIKE PEPTIDE 5 A CHAIN, PROBABLE INSULIN-LIKE PEPTIDE 5 B CHAIN | Authors: | Kulahin, N, Schluckebier, G, Sajid, W, De Meyts, P. | Deposit date: | 2009-04-15 | Release date: | 2010-05-26 | Last modified: | 2012-04-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Biological Properties of the Drosophila Insulin-Like Peptide 5 Show Evolutionary Conservation. J.Biol.Chem., 286, 2011
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2VK0
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![BU of 2vk0 by Molmil](/molmil-images/mine/2vk0) | Crystal structure form ultalente insulin microcrystals | Descriptor: | 4-HYDROXY-BENZOIC ACID METHYL ESTER, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. | Deposit date: | 2007-12-14 | Release date: | 2008-09-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Ultralente--A Microcrystalline Insulin Suspension. Proteins, 74, 2009
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2OMG
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2OLZ
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2OM0
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![BU of 2om0 by Molmil](/molmil-images/mine/2om0) | Structure of human insulin in presence of urea at pH 6.5 | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Norrman, M, Schluckebier, G. | Deposit date: | 2007-01-20 | Release date: | 2007-12-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. Bmc Struct.Biol., 7, 2007
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2OLY
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2OM1
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2OMH
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2OMI
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![BU of 2omi by Molmil](/molmil-images/mine/2omi) | |
1TRQ
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1G38
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![BU of 1g38 by Molmil](/molmil-images/mine/1g38) | ADENINE-SPECIFIC METHYLTRANSFERASE M. TAQ I/DNA COMPLEX | Descriptor: | 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... | Authors: | Goedecke, K, Pignot, M, Goody, R.S, Scheidig, A.J, Weinhold, E. | Deposit date: | 2000-10-23 | Release date: | 2001-03-05 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog. Nat.Struct.Biol., 8, 2001
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2IBS
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![BU of 2ibs by Molmil](/molmil-images/mine/2ibs) | Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position | Descriptor: | 5'-D(*GP*AP*CP*AP*TP*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... | Authors: | Pljevaljcic, G, Lenz, T, Scheidig, A.J, Weinhold, E. | Deposit date: | 2006-09-12 | Release date: | 2007-05-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence J.Am.Chem.Soc., 129, 2007
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2IBT
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![BU of 2ibt by Molmil](/molmil-images/mine/2ibt) | Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position | Descriptor: | 5'-D(*GP*AP*CP*AP*(3DR)P*CP*GP*(6MA)P*AP*C)-3', 5'-D(*GP*TP*TP*CP*GP*(2PR)P*TP*GP*TP*C)-3', 5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE, ... | Authors: | Lenz, T, Scheidig, A.J, Weinhold, E. | Deposit date: | 2006-09-12 | Release date: | 2007-05-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | 2-Aminopurine Flipped into the Active Site of the Adenine-Specific DNA Methyltransferase M.TaqI: Crystal Structures and Time-Resolved Fluorescence J.Am.Chem.Soc., 129, 2007
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2IH4
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2IH2
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