2IH2
Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 5-methylpyrimidin-2(1H)-one at the target base partner position
Summary for 2IH2
Entry DOI | 10.2210/pdb2ih2/pdb |
Related | 1AQI 1AQJ 1G38 2ADM 2IBS 2IBT 2IH4 2IH5 |
Descriptor | 5'-D(*GP*TP*TP*CP*GP*AP*TP*GP*TP*C)-3', 5'-D(*GP*AP*CP*AP*(5PY)P*CP*GP*(6MA)P*AP*C)-3', Modification methylase TaqI, ... (6 entities in total) |
Functional Keywords | dna, dna methyltransferase, target base partner, 5-methylpyrimidin-2(1h)-one, base flipping, nucleotide flipping, transferase-dna complex, transferase/dna |
Biological source | Thermus aquaticus More |
Total number of polymer chains | 6 |
Total formula weight | 109149.71 |
Authors | Lenz, T.,Scheidig, A.J.,Weinhold, E. (deposition date: 2006-09-25, release date: 2007-11-13, Last modification date: 2023-08-30) |
Primary citation | Lenz, T.,Scheidig, A.J.,Weinhold, E. Influence of the target base partner on the methylation rate of the adenine-specific DNA methyltransferase M.TaqI To be Published, |
Experimental method | X-RAY DIFFRACTION (1.61 Å) |
Structure validation
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