Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006304 | biological_process | DNA modification |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0009007 | molecular_function | site-specific DNA-methyltransferase (adenine-specific) activity |
| A | 0009307 | biological_process | DNA restriction-modification system |
| A | 0032259 | biological_process | methylation |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0006304 | biological_process | DNA modification |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0009007 | molecular_function | site-specific DNA-methyltransferase (adenine-specific) activity |
| D | 0009307 | biological_process | DNA restriction-modification system |
| D | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE NEA A 2001 |
| Chain | Residue |
| A | VAL21 |
| A | ASN105 |
| A | PRO107 |
| A | PHE146 |
| A | GOL3002 |
| A | HOH3048 |
| A | HOH3072 |
| A | HOH3144 |
| A | HOH3168 |
| A | HOH3234 |
| B | DA6 |
| A | ALA47 |
| A | GLU71 |
| A | ILE72 |
| A | ASP73 |
| A | ALA76 |
| A | ALA88 |
| A | ASP89 |
| A | PHE90 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NEA D 2002 |
| Chain | Residue |
| D | VAL21 |
| D | ALA47 |
| D | GLU71 |
| D | ILE72 |
| D | ASP73 |
| D | ALA88 |
| D | ASP89 |
| D | PHE90 |
| D | ASN105 |
| D | PRO107 |
| D | PHE146 |
| D | GOL3003 |
| D | HOH3066 |
| D | HOH3164 |
| D | HOH3173 |
| D | HOH3205 |
| E | DA6 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL C 3001 |
| Chain | Residue |
| A | LYS139 |
| A | ASP173 |
| A | HOH3060 |
| A | HOH3137 |
| B | DG1 |
| B | DT3 |
| C | DA19 |
| C | DC20 |
| C | HOH3007 |
| C | HOH3038 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 3002 |
| Chain | Residue |
| A | TYR129 |
| A | LEU142 |
| A | NEA2001 |
| A | HOH3255 |
| A | HOH3381 |
| A | HOH3420 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 3003 |
| Chain | Residue |
| D | TYR129 |
| D | LEU142 |
| D | NEA2002 |
| D | HOH3338 |
| D | HOH3519 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 3004 |
| Chain | Residue |
| A | LYS277 |
| A | HOH3103 |
| D | ARG58 |
| D | THR63 |
| D | TYR65 |
| D | PHE67 |
| D | TRP82 |
| D | HOH3416 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 3005 |
| Chain | Residue |
| D | LEU192 |
| D | THR220 |
| D | GLN221 |
| D | GLU222 |
| D | HOH3014 |
| D | HOH3321 |
Functional Information from PROSITE/UniProt
| site_id | PS00092 |
| Number of Residues | 7 |
| Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. ILGNPPY |
| Chain | Residue | Details |
| A | ILE102-TYR108 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | THR23 | |
| D | PRO107 | |
| A | GLU45 | |
| A | GLU71 | |
| A | ASP89 | |
| A | PRO107 | |
| D | THR23 | |
| D | GLU45 | |
| D | GLU71 | |
| D | ASP89 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Important for catalytic activity => ECO:0007744|PDB:2ADM |
| Chain | Residue | Details |
| A | ASN105 | |
| A | TYR108 | |
| D | ASN105 | |
| D | TYR108 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Important for catalytic activity; via amide nitrogen => ECO:0007744|PDB:2ADM |
| Chain | Residue | Details |
| A | PRO106 | |
| D | PRO106 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 2adm |
| Chain | Residue | Details |
| A | PRO106 | |
| A | ASN105 | |
| A | TYR108 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 2adm |
| Chain | Residue | Details |
| D | PRO106 | |
| D | ASN105 | |
| D | TYR108 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 46 |
| Chain | Residue | Details |
| A | ASN105 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| A | PRO106 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| A | TYR108 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| A | PHE196 | steric role |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 46 |
| Chain | Residue | Details |
| D | ASN105 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| D | PRO106 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| D | TYR108 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| D | PHE196 | steric role |
