3QYA
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![BU of 3qya by Molmil](/molmil-images/mine/3qya) | Crystal structure of a red-emitter mutant of Lampyris turkestanicus luciferase | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Kheirabadi, M, Gohlke, U, Hossein Khani, S, Heinemann, U, Naderi-Manesh, H. | Deposit date: | 2011-03-03 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal structure of native and a mutant of Lampyris turkestanicus luciferase implicate in bioluminescence color shift. Biochim.Biophys.Acta, 1834, 2013
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4TPJ
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![BU of 4tpj by Molmil](/molmil-images/mine/4tpj) | Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | Descriptor: | ALA-ALA-ALA, DODECYL-BETA-D-MALTOSIDE, Proton:oligopeptide symporter POT family, ... | Authors: | Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P. | Deposit date: | 2014-06-07 | Release date: | 2014-07-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
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4TPH
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![BU of 4tph by Molmil](/molmil-images/mine/4tph) | Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | Descriptor: | 3,5 DIBROMOTYROSINE, ALANINE, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P. | Deposit date: | 2014-06-07 | Release date: | 2014-07-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.155 Å) | Cite: | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
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4TPG
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![BU of 4tpg by Molmil](/molmil-images/mine/4tpg) | Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | Descriptor: | Ala-L-3-Br-Tyr-Ala, DODECYL-BETA-D-MALTOSIDE, Proton:oligopeptide symporter POT family, ... | Authors: | Guettou, F, Quistgaard, E.M, Raba, M, Moberg, P, Low, C, Nordlund, P. | Deposit date: | 2014-06-07 | Release date: | 2014-07-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.91 Å) | Cite: | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
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6C8H
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![BU of 6c8h by Molmil](/molmil-images/mine/6c8h) | Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of gadolinium | Descriptor: | GADOLINIUM ATOM, Transient receptor potential cation channel, subfamily V, ... | Authors: | Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P. | Deposit date: | 2018-01-24 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (6.5 Å) | Cite: | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms. Nat. Struct. Mol. Biol., 25, 2018
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6C8G
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![BU of 6c8g by Molmil](/molmil-images/mine/6c8g) | Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of barium | Descriptor: | BARIUM ION, Transient receptor potential cation channel, subfamily V, ... | Authors: | Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P. | Deposit date: | 2018-01-24 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (6.31 Å) | Cite: | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms. Nat. Struct. Mol. Biol., 25, 2018
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6C8F
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![BU of 6c8f by Molmil](/molmil-images/mine/6c8f) | Crystal structure of Transient Receptor Potential (TRP) channel TRPV4 in the presence of cesium | Descriptor: | CESIUM ION, Transient receptor potential cation channel, subfamily V, ... | Authors: | Deng, Z, Paknejad, N, Maksaev, G, Sala-Rabanal, M, Nichols, C.G, Hite, R.K, Yuan, P. | Deposit date: | 2018-01-24 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (6.5 Å) | Cite: | Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms. Nat. Struct. Mol. Biol., 25, 2018
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2YR5
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![BU of 2yr5 by Molmil](/molmil-images/mine/2yr5) | Crystal structure of L-phenylalanine oxidase from Psuedomonas sp.P501 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Pro-enzyme of L-phenylalanine oxidase, ... | Authors: | Ida, K, Kurabayashi, M, Suguro, M, Hikima, T, Yamamoto, M, Suzuki, H. | Deposit date: | 2007-04-02 | Release date: | 2008-04-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural basis of proteolytic activation of L-phenylalanine oxidase from Pseudomonas sp. P-501. J.Biol.Chem., 283, 2008
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2YR4
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![BU of 2yr4 by Molmil](/molmil-images/mine/2yr4) | Crystal structure of L-phenylalanine oxiase from Psuedomonas sp. P-501 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Pro-enzyme of L-phenylalanine oxidase, SULFATE ION | Authors: | Ida, K, Kurabayashi, M, Suguro, M, Suzuki, H. | Deposit date: | 2007-04-02 | Release date: | 2008-04-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of proteolytic activation of L-phenylalanine oxidase from Pseudomonas sp. P-501. J.Biol.Chem., 283, 2008
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2YR6
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![BU of 2yr6 by Molmil](/molmil-images/mine/2yr6) | Crystal structure of L-phenylalanine oxidase from Psuedomonas sp.P501 | Descriptor: | 2-AMINOBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Ida, K, Kurabayashi, M, Suguro, M, Suzuki, H. | Deposit date: | 2007-04-02 | Release date: | 2008-04-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural basis of proteolytic activation of L-phenylalanine oxidase from Pseudomonas sp. P-501. J.Biol.Chem., 283, 2008
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4M46
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![BU of 4m46 by Molmil](/molmil-images/mine/4m46) | |
7KNW
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![BU of 7knw by Molmil](/molmil-images/mine/7knw) | Crystal structure of SND1 in complex with C-26-A2 | Descriptor: | 5-chloro-2-methoxy-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide, GLYCEROL, Staphylococcal nuclease domain-containing protein 1 | Authors: | Kang, Y. | Deposit date: | 2020-11-06 | Release date: | 2021-12-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. Nat Cancer, 3, 2022
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7KNX
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![BU of 7knx by Molmil](/molmil-images/mine/7knx) | Crystal structure of SND1 in complex with C-26-A6 | Descriptor: | 5-chloro-2-methoxy-N-(2-methyl[1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide, GLYCEROL, Staphylococcal nuclease domain-containing protein 1, ... | Authors: | Kang, Y. | Deposit date: | 2020-11-06 | Release date: | 2021-12-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. Nat Cancer, 3, 2022
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6YLC
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![BU of 6ylc by Molmil](/molmil-images/mine/6ylc) | Biochemical, Cellular and Structural Characterization of Novel ERK3 Inhibitors | Descriptor: | 5-fluoranyl-2-[5-[[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]amino]-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]benzenecarbonitrile, Mitogen-activated protein kinase 6 | Authors: | Graedler, U. | Deposit date: | 2020-04-07 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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6YKY
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![BU of 6yky by Molmil](/molmil-images/mine/6yky) | Biochemical, Cellular and Structural Characterization of Novel ERK3 Inhibitors | Descriptor: | 3-(4-methoxyphenyl)-~{N}-[(3~{R})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine, Mitogen-activated protein kinase 6 | Authors: | Graedler, U. | Deposit date: | 2020-04-06 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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6YLL
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![BU of 6yll by Molmil](/molmil-images/mine/6yll) | Biochemical, Cellular and Structural Characterization of Novel ERK3 Inhibitors | Descriptor: | Mitogen-activated protein kinase 6, ~{N}4-[3-(4-methoxyphenyl)-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]cyclohexane-1,4-diamine | Authors: | Graedler, U. | Deposit date: | 2020-04-07 | Release date: | 2020-09-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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8FYG
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![BU of 8fyg by Molmil](/molmil-images/mine/8fyg) | Crystal structure of Hyaluronate lyase A from Cutibacterium acnes | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Hyaluronate lyase | Authors: | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | Deposit date: | 2023-01-26 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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8FNX
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![BU of 8fnx by Molmil](/molmil-images/mine/8fnx) | Crystal structure of Hyaluronate lyase B from Cutibacterium acnes | Descriptor: | GLYCEROL, Hyaluronate lyase, PHOSPHATE ION | Authors: | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | Deposit date: | 2022-12-28 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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8G0O
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![BU of 8g0o by Molmil](/molmil-images/mine/8g0o) | Crystal structure of Y281F mutant of Hyaluronate lyase B from Cutibacterium acnes | Descriptor: | Hyaluronate lyase | Authors: | Katiki, M, McNally, R, Chatterjee, A, Hajam, I.A, Liu, G.Y, Murali, R. | Deposit date: | 2023-02-01 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14, 2023
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8DVG
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![BU of 8dvg by Molmil](/molmil-images/mine/8dvg) | Structure of KRAS WT(7-16)-HLA-A*03:01 | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, HLA class I histocompatibility antigen, ... | Authors: | Wright, K.M, Miller, M, Gabelli, S.B. | Deposit date: | 2022-07-28 | Release date: | 2023-07-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.594 Å) | Cite: | Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nat Commun, 14, 2023
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5Y30
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![BU of 5y30 by Molmil](/molmil-images/mine/5y30) | Crystal structure of LGI1 LRR domain | Descriptor: | Leucine-rich glioma-inactivated protein 1 | Authors: | Yamagata, A, Fukai, S. | Deposit date: | 2017-07-27 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.781 Å) | Cite: | Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nat Commun, 9, 2018
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5Y2Z
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![BU of 5y2z by Molmil](/molmil-images/mine/5y2z) | Crystal structure of human LGI1 EPTP-ADAM22 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A, Fukai, S. | Deposit date: | 2017-07-27 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nat Commun, 9, 2018
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7CQF
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![BU of 7cqf by Molmil](/molmil-images/mine/7cqf) | |
5TSZ
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![BU of 5tsz by Molmil](/molmil-images/mine/5tsz) | Crystal structure of Plasmodium vivax CelTOS | Descriptor: | Pv cell-traversal protein, SODIUM ION | Authors: | Tolia, N.H, Jimah, J.R. | Deposit date: | 2016-10-31 | Release date: | 2016-12-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption. Elife, 5, 2016
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5Y31
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![BU of 5y31 by Molmil](/molmil-images/mine/5y31) | Crystal structure of human LGI1-ADAM22 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... | Authors: | Yamagata, A, Fukai, S. | Deposit date: | 2017-07-27 | Release date: | 2018-05-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (7.125 Å) | Cite: | Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nat Commun, 9, 2018
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