6YKY
Biochemical, Cellular and Structural Characterization of Novel ERK3 Inhibitors
Summary for 6YKY
| Entry DOI | 10.2210/pdb6yky/pdb |
| Descriptor | Mitogen-activated protein kinase 6, 3-(4-methoxyphenyl)-~{N}-[(3~{R})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (3 entities in total) |
| Functional Keywords | mitogen-activated protein kinase 6, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 146328.39 |
| Authors | Graedler, U. (deposition date: 2020-04-06, release date: 2020-09-23, Last modification date: 2024-01-24) |
| Primary citation | Gradler, U.,Busch, M.,Leuthner, B.,Raba, M.,Burgdorf, L.,Lehmann, M.,Linde, N.,Esdar, C. Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors. Bioorg.Med.Chem.Lett., 30:127551-127551, 2020 Cited by PubMed: 32927028DOI: 10.1016/j.bmcl.2020.127551 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
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