5Y31

Crystal structure of human LGI1-ADAM22 complex

Summary for 5Y31

• Entry DOI: 10.2210/pdb5y31/pdb
• Descriptor: Disintegrin and metalloproteinase domain-containing protein 22, Leucine-rich glioma-inactivated protein 1, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: epilepsy, synapse, adam, eptp, wd40, cell adhesion
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 237280.73

Authors

Yamagata, A.,Fukai, S. (deposition date: 2017-07-27, release date: 2018-05-02, Last modification date: 2020-07-29)

• Primary citation: Yamagata, A.,Miyazaki, Y.,Yokoi, N.,Shigematsu, H.,Sato, Y.,Goto-Ito, S.,Maeda, A.,Goto, T.,Sanbo, M.,Hirabayashi, M.,Shirouzu, M.,Fukata, Y.,Fukata, M.,Fukai, S.; Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.; Nat Commun, 9:1546-1546, 2018; PubMed: 29670100; DOI: 10.1038/s41467-018-03947-w

Experimental method

X-RAY DIFFRACTION (7.125 Å)