8G0O

Crystal structure of Y281F mutant of Hyaluronate lyase B from Cutibacterium acnes

Summary for 8G0O

Entry DOI	10.2210/pdb8g0o/pdb
Descriptor	Hyaluronate lyase (2 entities in total)
Functional Keywords	polysaccharide lyase, glycosaminoglycan (gag) lyase, hyaluronate lyase, inflammation, lyase
Biological source	Cutibacterium acnes HL110PA3
Total number of polymer chains	2
Total formula weight	166925.98
Authors	Katiki, M.,McNally, R.,Chatterjee, A.,Hajam, I.A.,Liu, G.Y.,Murali, R. (deposition date: 2023-02-01, release date: 2023-12-13)
Primary citation	Hajam, I.A.,Katiki, M.,McNally, R.,Lazaro-Diez, M.,Kolar, S.,Chatterjee, A.,Gonzalez, C.,Paulchakrabarti, M.,Choudhury, B.,Caldera, J.R.,Desmond, T.,Tsai, C.M.,Du, X.,Li, H.,Murali, R.,Liu, G.Y. Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14:8061-8061, 2023 Cited by PubMed: 38052825 DOI: 10.1038/s41467-023-43833-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation