8FNX

Crystal structure of Hyaluronate lyase B from Cutibacterium acnes

Summary for 8FNX

Entry DOI	10.2210/pdb8fnx/pdb
Descriptor	Hyaluronate lyase, GLYCEROL, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	polysaccharide lyase, glycosaminoglycan (gag) lyase, hyaluronate lyase, inflammation, lyase
Biological source	Cutibacterium acnes HL110PA3
Total number of polymer chains	1
Total formula weight	84313.59
Authors	Katiki, M.,McNally, R.,Chatterjee, A.,Hajam, I.A.,Liu, G.Y.,Murali, R. (deposition date: 2022-12-28, release date: 2023-12-13)
Primary citation	Hajam, I.A.,Katiki, M.,McNally, R.,Lazaro-Diez, M.,Kolar, S.,Chatterjee, A.,Gonzalez, C.,Paulchakrabarti, M.,Choudhury, B.,Caldera, J.R.,Desmond, T.,Tsai, C.M.,Du, X.,Li, H.,Murali, R.,Liu, G.Y. Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun, 14:8061-8061, 2023 Cited by PubMed: 38052825 DOI: 10.1038/s41467-023-43833-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation