8DVG

Structure of KRAS WT(7-16)-HLA-A*03:01

Summary for 8DVG

• Entry DOI: 10.2210/pdb8dvg/pdb
• EMDB information: 25427
• Descriptor: HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, VAL-VAL-VAL-GLY-ALA-GLY-GLY-VAL-GLY-LYS, ... (6 entities in total)
• Functional Keywords: immunotherapy, mhc-i, hla-a3, kras, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 50519.70

Authors

Wright, K.M.,Miller, M.,Gabelli, S.B. (deposition date: 2022-07-28, release date: 2023-07-19, Last modification date: 2023-10-25)

• Primary citation: Wright, K.M.,DiNapoli, S.R.,Miller, M.S.,Aitana Azurmendi, P.,Zhao, X.,Yu, Z.,Chakrabarti, M.,Shi, W.,Douglass, J.,Hwang, M.S.,Hsiue, E.H.,Mog, B.J.,Pearlman, A.H.,Paul, S.,Konig, M.F.,Pardoll, D.M.,Bettegowda, C.,Papadopoulos, N.,Kinzler, K.W.,Vogelstein, B.,Zhou, S.,Gabelli, S.B.; Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.; Nat Commun, 14:5063-5063, 2023; PubMed: 37604828; DOI: 10.1038/s41467-023-40821-w

Experimental method

X-RAY DIFFRACTION (2.594 Å)