5Y2Z
Crystal structure of human LGI1 EPTP-ADAM22 complex
Summary for 5Y2Z
| Entry DOI | 10.2210/pdb5y2z/pdb |
| Descriptor | Disintegrin and metalloproteinase domain-containing protein 22, Leucine-rich glioma-inactivated protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
| Functional Keywords | epilepsy, synapse, adam, eptp, wd40, cell adhesion |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 12 |
| Total formula weight | 583485.08 |
| Authors | Yamagata, A.,Fukai, S. (deposition date: 2017-07-27, release date: 2018-05-02, Last modification date: 2023-11-22) |
| Primary citation | Yamagata, A.,Miyazaki, Y.,Yokoi, N.,Shigematsu, H.,Sato, Y.,Goto-Ito, S.,Maeda, A.,Goto, T.,Sanbo, M.,Hirabayashi, M.,Shirouzu, M.,Fukata, Y.,Fukata, M.,Fukai, S. Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nat Commun, 9:1546-1546, 2018 Cited by PubMed: 29670100DOI: 10.1038/s41467-018-03947-w PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.67 Å) |
Structure validation
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