5Y2Z
Crystal structure of human LGI1 EPTP-ADAM22 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| C | 0004222 | molecular_function | metalloendopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008237 | molecular_function | metallopeptidase activity |
| E | 0004222 | molecular_function | metalloendopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| E | 0008237 | molecular_function | metallopeptidase activity |
| G | 0004222 | molecular_function | metalloendopeptidase activity |
| G | 0006508 | biological_process | proteolysis |
| G | 0008237 | molecular_function | metallopeptidase activity |
| I | 0004222 | molecular_function | metalloendopeptidase activity |
| I | 0006508 | biological_process | proteolysis |
| I | 0008237 | molecular_function | metallopeptidase activity |
| K | 0004222 | molecular_function | metalloendopeptidase activity |
| K | 0006508 | biological_process | proteolysis |
| K | 0008237 | molecular_function | metallopeptidase activity |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1194 |
| Details | Domain: {"description":"Peptidase M12B","evidences":[{"source":"PROSITE-ProRule","id":"PRU00276","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 522 |
| Details | Domain: {"description":"Disintegrin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00068","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 222 |
| Details | Domain: {"description":"EGF-like"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 17 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19692335","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 252 |
| Details | Repeat: {"description":"EAR 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00075","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 252 |
| Details | Repeat: {"description":"EAR 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00075","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 282 |
| Details | Repeat: {"description":"EAR 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00075","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 294 |
| Details | Repeat: {"description":"EAR 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00075","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 258 |
| Details | Repeat: {"description":"EAR 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00075","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 252 |
| Details | Repeat: {"description":"EAR 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00075","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 12 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"EAR 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00075","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
