5Y2Z

Crystal structure of human LGI1 EPTP-ADAM22 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
C	0004222	molecular_function	metalloendopeptidase activity
C	0006508	biological_process	proteolysis
C	0008237	molecular_function	metallopeptidase activity
E	0004222	molecular_function	metalloendopeptidase activity
E	0006508	biological_process	proteolysis
E	0008237	molecular_function	metallopeptidase activity
G	0004222	molecular_function	metalloendopeptidase activity
G	0006508	biological_process	proteolysis
G	0008237	molecular_function	metallopeptidase activity
I	0004222	molecular_function	metalloendopeptidase activity
I	0006508	biological_process	proteolysis
I	0008237	molecular_function	metallopeptidase activity
K	0004222	molecular_function	metalloendopeptidase activity
K	0006508	biological_process	proteolysis
K	0008237	molecular_function	metallopeptidase activity

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CvCnrHwiGSdC

Chain	Residue	Details
A	CYS700-CYS711

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site_id	PS00427
Number of Residues	20
Details	DISINTEGRIN_1 Disintegrins signature. CsdGlCCk.KCkFqpmgtvCR

Chain	Residue	Details
A	CYS485-ARG504

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
B	ASN277
J	ASN422
L	ASN277
L	ASN422
I	ASN519
I	ASN634
I	ASN675
K	ASN519
K	ASN634
K	ASN675
B	ASN422
D	ASN277
D	ASN422
F	ASN277
F	ASN422
H	ASN277
H	ASN422
J	ASN277

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